Imperial College London

This study tests whether cooling the body of babies who had a mild lack of oxygen at birth can improve their thinking and learning skills by age 2. About 426 full-term newborns will be randomly assigned to either whole-body cooling or normal temperature care. The goal is to see i…

This study is testing a new breath test to help detect pancreatic cancer earlier. Pancreatic cancer is often found late because its symptoms are similar to common illnesses. The test looks for tiny molecules in the breath that are made by cancer cells. Researchers will study abou…

This study looks at whether buying over-the-counter pain relievers and digestive aids can be an early warning sign for ten types of cancer, including pancreatic, colon, and ovarian cancer. Researchers will compare the shopping habits of 2,900 people recently diagnosed with cancer…

This study looks at whether giving blood-thinning medicine after varicose vein surgery can prevent dangerous blood clots. About 1 in 50 people get a clot after this keyhole procedure, which can cause pain, swelling, or even travel to the lungs. The trial will enroll 6,660 adults …

This study looks at whether wearing compression stockings in the hospital, on top of taking blood-thinning medication, can further reduce the risk of dangerous blood clots after high-risk surgeries like cancer or joint replacement. About 8,600 adults will be randomly assigned to …

This study tests a wearable belt that tracks muscle activity and gives real-time feedback through a phone app during core exercises. About 40 adults with long-term lower back pain will use the belt along with standard care, or just standard care alone, for 8 weeks. The goal is to…

This study watches 70 people who already need a heart artery procedure. It measures blood flow and pressure while pacing the heart to see how well they tolerate ventricular tachycardia. The goal is to understand if blocked arteries or tiny vessel problems make the rhythm harder t…

This study aims to understand why the common cold (rhinovirus) causes severe flare-ups in people with COPD. Researchers will intentionally infect 50 volunteers (some with COPD, some healthy) with the virus in a controlled setting. By comparing their immune responses, they hope to…

This study looks at how the body processes high doses of the steroid prednisolone in people with inflammatory diseases like thyroid eye disease, asthma, and vasculitis. Researchers will measure drug levels in the blood over time to compare short-term and long-term use. The goal i…

This study follows 600 people over age 65 for three years to understand how Alzheimer's disease develops in the brain before memory problems become obvious. Researchers will test thinking skills and take blood samples each year. The goal is to find early warning signs that could …

This study explores whether a low, non-hallucinogenic dose of psilocybin (the active ingredient in magic mushrooms) can make a mental imagery therapy more effective for young people aged 16-25 who self-harm. The therapy, called Imagery Re-Scripting, helps replace upsetting mental…

This study looks at 100 older adults with normal pressure hydrocephalus (NPH) to find out why some improve after a shunt surgery while others do not. Researchers will use brain scans, blood and spinal fluid tests, and wearable activity monitors to compare those who respond to sur…