Scientists measure exact moment blockages trigger angina
NCT ID NCT07386418
First seen Feb 04, 2026 · Last updated Jun 23, 2026 · Updated 21 times
Summary
This study, called ORBITA-SOLAR, aims to find out if different narrowed arteries in the heart cause chest pain (angina) at different levels of blood flow reduction. Sixty people with stable angina who need stents will have a tiny balloon inflated inside each stent while they exercise on a bike. The researchers will measure the exact point when chest pain starts, to see if the threshold varies by location. This is an observational study, not a treatment trial.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Imperial College Healthcare NHS Trust
RECRUITINGLondon, United Kingdom
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Mid and South Essex NHS Foundation Trust
NOT_YET_RECRUITINGBasildon, United Kingdom
Contact Email: •••••@•••••
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Portsmouth Hospitals University NHS Trust
NOT_YET_RECRUITINGPortsmouth, United Kingdom
Contact Email: •••••@•••••
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Royal Free London NHS Foundation Trust
NOT_YET_RECRUITINGLondon, United Kingdom
Contact Email: •••••@•••••
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St George's University Hospitals NHS Foundation Trust
NOT_YET_RECRUITINGLondon, United Kingdom
Contact Email: •••••@•••••
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University Hospitals Dorset NHS Foundation Trust
NOT_YET_RECRUITINGBournemouth, United Kingdom
Contact Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could help doctors better understand which blockages cause symptoms and guide more targeted treatments for stable angina.
What could go wrong
This is a small, early-stage observational study (60 people) that measures symptoms in a controlled lab setting. Results may not apply to all patients or change current treatment.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.