Imperial College London
Clinical trials sponsored by Imperial College London, explained in plain language.
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New hope for tough colorectal cancer: drug trial uses ultrasound to predict success
Disease control CompletedThis study tested a drug called axitinib against a placebo in 52 people with advanced colorectal cancer that had spread to the liver and stopped responding to chemotherapy. The goal was to see if axitinib could help patients live longer and to test a new ultrasound method that me…
Phase: PHASE2 • Sponsor: Imperial College London • Aim: Disease control
Last updated May 01, 2026 15:57 UTC
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Radiation beads show promise for liver tumors in small trial
Disease control CompletedThis study tested a treatment called TheraSphere for people with neuroendocrine tumors that have spread to the liver and cannot be removed by surgery. TheraSphere uses tiny radioactive beads delivered directly to the liver to kill cancer cells. The trial included 24 adults who ha…
Phase: PHASE2 • Sponsor: Imperial College London • Aim: Disease control
Last updated Apr 29, 2026 15:03 UTC
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Can these drugs stop COVID-19 pneumonia from turning severe?
Disease control CompletedThis study tested two drugs, ruxolitinib and fostamatinib, in hospitalized adults with mild to moderate COVID-19 pneumonia. The goal was to see if either drug could prevent the disease from becoming severe, such as needing a breathing machine. Participants received the drug for 1…
Phase: PHASE1, PHASE2 • Sponsor: Imperial College London • Aim: Disease control
Last updated Apr 29, 2026 15:03 UTC
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Blow into this tube: breath test may spot liver disease before It's too late
Diagnosis CompletedThis study looked at whether a breath test could help find liver scarring (fibrosis), severe scarring (cirrhosis), or liver cancer early. 56 adults with known or suspected liver problems gave a breath sample after fasting. Scientists then analyzed the breath for unique chemical m…
Sponsor: Imperial College London • Aim: Diagnosis
Last updated May 01, 2026 15:58 UTC
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HPV vaccine during cervical procedure may cut infection risk
Prevention CompletedThis study tested whether giving the Gardasil 9 HPV vaccine at the same time as a cone biopsy (removing abnormal cervical cells) helps clear HPV and prevents future infections and high-grade cervical changes. About 1,100 women aged 18-55 with moderate to severe cervical cell chan…
Phase: PHASE3 • Sponsor: Imperial College London • Aim: Prevention
Last updated May 01, 2026 15:57 UTC
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Diabetes drug tested for lung clot inflammation
Knowledge-focused CompletedThis study looked at whether semaglutide, a medicine used for diabetes, changes certain blood markers related to inflammation in people who recently had a pulmonary embolism (a blood clot in the lung). 18 adults with acute pulmonary embolism took semaglutide, and researchers meas…
Sponsor: Imperial College London • Aim: Knowledge-focused
Last updated May 01, 2026 15:59 UTC
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Heart-Healthy supplement tested against common painkiller risks
Knowledge-focused CompletedThis study tested whether the amino acid arginine could prevent blood vessel damage caused by the NSAID painkiller celecoxib. 44 healthy men took either arginine or a placebo alongside celecoxib for 7 days. Researchers measured changes in blood vessel function and stiffness to se…
Phase: PHASE4 • Sponsor: Imperial College London • Aim: Knowledge-focused
Last updated May 01, 2026 15:59 UTC
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Scientists probe why RSV hits seniors harder
Knowledge-focused CompletedThis study looked at how the immune system of older adults (ages 60-75) responds to the respiratory syncytial virus (RSV). Researchers exposed 28 healthy volunteers to a controlled dose of RSV to track their immune reactions and any side effects. The goal is to understand why old…
Phase: NA • Sponsor: Imperial College London • Aim: Knowledge-focused
Last updated May 01, 2026 15:58 UTC
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Cancer Patients' COVID-19 journey revealed in massive study
Knowledge-focused CompletedThis study looked at 3820 adults with cancer who also had COVID-19. Researchers collected routine medical data to describe symptoms and identify factors that affect survival. The goal was to better understand how the virus impacts cancer patients, without testing any new treatmen…
Sponsor: Imperial College London • Aim: Knowledge-focused
Last updated Apr 29, 2026 15:03 UTC