Smart insulin pump could transform diabetes care for kidney patients

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 1\. Age 18-70 years inclusive * 2\. Type 1 diabetes of at least 1-year duration or insulin-requiring type 2 diabetes managed with multiple daily injections (MDI \[ie separate rapid-acting and basal insulin injections\]) or insulin pump therapy (CSII) * 3\. The HbA1c \<10.5% (\<91 mmol/mol) * 4\. The total daily dose of insulin \<200Units * 5\. The participant is willing and able to implement the study requirements. * 6\. Participant has advanced renal disease (Group A: Stage 3b or greater renal failure (eGFR \<45millilitres/minute/1.73m2); Group B: ESKD requiring peritoneal dialysis; Group C: ESKD requiring haemodialysis * 7\. Participants (and carer where applicable) should be able to speak and understand English sufficiently for safe study conduct * 8\. The participant has internet or smartphone access, enabling upload of the 780G system data to cloud-based software Exclusion Criteria: * 1\. The participant is already using an AID system * 2\. The participant is treated with sulphonylureas (SGLT2 inhibitors, metformin, and GLP1 analogues may be used within regulatory guidelines) in pre-dialysis participants (Group A). In Groups B \& C, noninsulin glucose-lowering therapies are not permitted, with the exception of GLP1 agonists used in preparation for transplantation * 3\. The participant has a recent history of diabetic ketoacidosis (\<6 months) * 4\. The use of systemic steroid therapy within the past four weeks (stable doses of steroids for \>8 weeks permitted) * 5\. The participant has significant cognitive impairment or major psychiatric history affecting safe study conduct * 6\. Known significant allergy to tape/ adhesives * 7\. Women who are pregnant or planning pregnancy * 8\. The participant has an active major life-threatening illness limiting the participants life expectancy to \<6 months * 9\. The participant is on hydroxyurea treatment or taking regular / daily paracetamol treatment (sensor interference)