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Heart rhythm study probes why some patients tolerate VT better than others

NCT ID NCT05841199

Knowledge-focused Sponsor: Imperial College London Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This observational study at Imperial College London will enroll 70 people undergoing heart catheterization to understand why some patients tolerate ventricular tachycardia (VT) better than others. Researchers will measure blood pressure and blood flow in the heart during simulated fast heart rates. The goal is to see how coronary artery disease and stents affect VT tolerability.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help doctors better predict which patients are at risk from dangerous heart rhythms and guide treatment decisions.
What could go wrong
This is an observational study, not a treatment trial. It will not directly test a new therapy, and results may not change current practice immediately.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 70 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2023

Expected to finish

Jun 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adults referred for coronary angiography or coronary angioplasty.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Able to give valid consent * Referred for coronary angiography or coronary angioplasty * Suitable for percutaneous physiological interrogation and PCI when clinically indicated Exclusion Criteria: * Unable to give valid consent * Pregnant or breastfeeding women * Unstable coronary artery disease (acute coronary syndrome) * Severe multivessel coronary artery disease suitable for coronary artery bypass grafting * Severe heart valve disease * Severe (NYHA IV) heart failure

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Conditions

The condition(s) this trial relates to.

coronary artery disorder coronary microvascular disorder heart failure Microvascular Angina ventricular tachycardia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Coronary artery disease Coronary microvascular disease Coronary microvascular dysfunction Heart failure Ventricular tachycardia

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Imperial College NHS Foundation Trust

    RECRUITING

    London, W12 0HS, United Kingdom

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