Beijing Tiantan Hospital

This study tests whether a procedure to remove blood clots from the brain can help people who have had a severe stroke recover more independence. The trial will include 308 adults aged 18 to 80 with a large stroke in the back of the brain. Participants will either receive the clo…

This study compares a new 'one-stop' emergency stroke unit that combines CT scans and treatment in one room to the usual step-by-step approach. It aims to see if faster diagnosis and treatment helps people with severe strokes recover better and be more independent after 90 days. …

This study tests whether adding a new drug called Tolecilimab to standard cholesterol-lowering therapy can lower a specific blood fat called lipoprotein(a) and reduce the chance of another stroke within 90 days. The trial includes 242 adults aged 35-80 who recently had a stroke o…

This early-stage trial tests an oral biologic called Gut-X-001 in 120 people with Alzheimer's disease. The goal is to see if it can improve thinking, daily function, and brain health, while checking for safety. The study also looks at how the treatment affects gut bacteria and bl…

This study tests whether a drug called ulinastatin can lower the chance of having a stroke after brain tumor surgery. Strokes, including ones that are hard to notice, are common after these operations. The trial will give 1,370 patients either ulinastatin or a placebo before and …

This study tests whether the antibiotic minocycline can improve recovery in adults who have had an ischemic stroke and received clot-busting medication. About 934 participants aged 18 to 80 will receive either minocycline or a placebo within hours of their stroke. The goal is to …

This study tests a new approach for people with a large brain bleed (lobar intracerebral hemorrhage). It combines a computer-guided, minimally invasive surgery to drain the clot with a clot-busting drug called tenecteplase. The goal is to see if this treatment helps more people r…

This study tests whether the drug cilostazol can reduce delayed brain injury in people who have had a bleeding aneurysm. About 316 adults will receive either cilostazol or a placebo to see if it helps prevent complications and improve recovery. The goal is to find a safe way to p…

This study tests whether two drugs, isosorbide mononitrate and butylphthalide, can reduce disability in people who recently had a lacunar (small vessel) stroke. About 3,156 adults aged 30 and older will take one or both drugs for up to a year. The goal is to see if these treatmen…

This study compares two ways to treat people having a severe stroke caused by a blocked large artery. One group goes straight to a special X-ray room (angiography suite) for treatment, while the other group gets standard CT or MRI scans first. The goal is to see if the direct rou…

This study tests whether tailoring blood pressure management based on the brain's collateral circulation (backup blood flow) can improve recovery in people who had a stroke and underwent a procedure to remove a clot. About 544 participants will be randomly assigned to either pers…

This study tests whether the drug anakinra can limit brain damage in people who have had a severe stroke and have already undergone a procedure to reopen a blocked artery. About 159 adults aged 18-80 will receive either standard care or anakinra at different doses. The goal is to…

This study tests whether adding the blood thinner tirofiban after standard stroke treatment helps people recover better. About 564 adults who had a stroke from a blocked large artery will be randomly assigned to get tirofiban or usual care. The goal is to see if more people can l…

This study tests whether Naoxuekang Dropping Pills, a Chinese herbal medicine, can reduce the risk of future strokes, heart attacks, or blood clots in people who recently had a brain bleed caused by high blood pressure. About 1,950 adults will receive either the herbal pill or a …

This study looks at whether raising blood pressure soon after surgery or coiling for a ruptured brain aneurysm can improve recovery in people with subarachnoid hemorrhage. About 750 adults aged 18-75 will have their blood pressure kept at a higher or lower target for 72 hours, th…

This study tests a new medicine called ongericimab, given as an injection, to see if it can lower bad cholesterol and prevent future strokes, heart attacks, or heart-related death in people who recently had a stroke. The trial will include about 4,810 adults who have a stroke wit…

This study tests a traditional Chinese medicine called Jiedu Huayu to see if it can lower the chance of another brain bleed or stroke in people with cerebral amyloid angiopathy (CAA). About 436 adults who recently had a small brain bleed will take either the herbal prescription o…

This study tests whether the drug levetiracetam can prevent seizures in adults after brain tumor surgery. About 558 participants will receive either the drug or a placebo, starting one hour before surgery and continuing for three months. The goal is to see if the drug reduces the…

This study looks at whether giving a stellate ganglion block (a nerve injection) before surgery can help patients with prolonged disorders of consciousness sleep better and possibly recover more. About 25 adults with intact skulls who need spinal cord stimulator implantation will…

This study tests whether a patch made from a patient's own platelet-rich plasma (PRP) works better than a standard whole blood patch to stop severe headaches caused by spontaneous spinal fluid leaks. About 218 adults who have not gotten better with rest or other simple treatments…

This study tests whether adding tizanidine to the standard drug pregabalin provides better pain relief for people with fibromyalgia, a condition causing widespread pain and fatigue. About 164 adults with daily pain will receive either the combo or pregabalin alone for 12 weeks. T…

This study tests whether a new form of the anti-inflammatory drug dexamethasone (dexamethasone palmitate) can better prevent moderate-to-severe pain after surgery compared to the standard version. About 446 adults having various surgeries will receive the drug before their operat…

This study tests whether injecting a steroid (triamcinolone) plus a numbing drug (ropivacaine) into the surgical site before video-assisted lung surgery can reduce pain better than the numbing drug alone. About 100 adults having lung surgery will be randomly assigned to one of tw…

This study tests a new therapy that uses a brain-computer interface (a device that reads brain signals) combined with mirror therapy (watching a video of your good arm moving) to help stroke survivors regain arm movement. The robot helps move the affected arm based on brain signa…

This study tests whether placing a loxoprofen sodium patch on the skin before thoracoscopic lung surgery can lower pain after the operation. About 156 adults aged 8 to 64 having lung surgery will be randomly assigned to get the patch or a placebo. The main goal is to see if the p…

This study tests whether placing a loxoprofen sodium patch on surgical cuts before laparoscopic surgery can lower pain and reduce the need for extra painkillers. About 134 adults having gallbladder, appendix, or hernia surgery will take part. The goal is to see if this simple ste…

This study tests if using scalp nerve blocks and a sedative drug called dexmedetomidine can reduce the need for strong opioid painkillers and prevent confusion after brain tumor surgery. About 2000 adults having elective brain surgery will be randomly assigned to one of four trea…

This study tests whether injecting a numbing medicine (ropivacaine) plus an anti-inflammatory steroid (triamcinolone) into surgical cuts before laparoscopic surgery reduces pain better than the numbing medicine alone. About 150 adults having gallbladder, appendix, or hernia surge…

This study tests whether a steroid medicine called dexamethasone palmitate can reduce pain from shingles and prevent long-term nerve pain. About 954 adults with severe shingles pain will receive the steroid by injection or standard care. The goal is to see if the steroid provides…

This study tests a new approach for people with severe, long-term insomnia that hasn't improved with standard treatments. Researchers will give a mild anesthetic to help patients sleep naturally and track sleep quality and safety over time. The goal is to see if this method can p…

This study tests a combination of pain medicines and local numbing to improve pain control after brain tumor surgery. The goal is to reduce the need for strong opioids, which can cause side effects and complications. About 2,000 adults having planned brain surgery will take part.…

This study looks at whether a combination of brain monitoring tools can predict strokes that happen during or after heart surgery. About 369 high-risk patients will be watched using special devices that track blood flow, brain activity, and oxygen levels. The goal is to see if th…

This study looks at people with brain arteriovenous malformations (AVMs) in the left side of the brain, which normally controls language. Surprisingly, many of these people have normal language skills, suggesting the right brain has taken over. Researchers will use MRI scans to u…