One-Stop stroke suite could save minutes and brains
NCT ID NCT07456228
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares a new 'one-stop' emergency stroke unit that combines CT scanning and treatment in one room to the usual process where scans and treatment happen in separate places. The goal is to see if this faster approach helps more people recover with little or no disability 90 days after a stroke. About 500 adults with suspected large-vessel blockage stroke arriving within 6 hours of symptoms will take part.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 500 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Mar 2026
An estimate. Start dates often move.
- Expected to finish
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Mar 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
It includes patients aged ≥18 years with a RACE score ≥4, a pre-stroke mRS score ≤1, and suspected intracranial LVO within 6 hours of onset. Hospitals in the exposure group utilize an Emergency Stroke Unit equipped with a sliding NeuAngio-CT/DSA hybrid suite, while control hospitals follow the conventional imaging workflow.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
* Inclusion Criteria: 1. Age ≥ 18 years; 2. Clinically diagnosed with acute ischemic stroke; 3. RACE score ≥ 4 points upon hospital arrival; 4. Time from symptom onset/last known normal to hospital arrival ≤ 6 hours; 5. Pre-stroke mRS score 0-1; 6. Informed consent signed by the patient or their legal representative. * Exclusion Criteria: 1. Hemorrhagic stroke diagnosed by cranial CT or MRI during this current episode; 2. Uncontrolled hypertension with medication (defined as systolic blood pressure \> 185 mmHg or diastolic blood pressure \> 110 mmHg) (Note: Patients may be included if blood pressure can be successfully reduced and maintained at an acceptable level with medication); 3. Known hereditary or acquired bleeding tendency, such as coagulation factor deficiency, or INR \> 3.0 or PT \> 3 times the normal range after anticoagulant therapy (Patients without a history of coagulation dysfunction or suspected coagulation dysfunction do not need to wait for laboratory results of INR or prothrombin time before enrollment); 4. Received heparin, low-molecular-weight heparin (e.g., dalteparin sodium), or thrombin inhibitors (e.g., bivalirudin, argatroban) within 24 hours with a history of coagulation disorders; 5. Baseline laboratory values: blood glucose \< 50 mg/dl (2.78 mmol/L) or \> 400 mg/dl (22.20 mmol/L), hemoglobin count \< 7 mmol/l (11.28 g/dl); platelet count \< 50,000/μl; 6. Patients with renal failure, defined as serum creatinine \> 3.0 mg/dl (264 μmol/l) (Note: Patients undergoing dialysis can be included regardless of serum creatinine level); 7. Cerebral embolism caused by septic emboli or bacterial endocarditis; 8. History of stroke within the past 3 months; 9. Seizure at stroke onset leading to diagnostic confusion and difficulty in accurate baseline RACE assessment; 10. History of previous neuropsychiatric disorders that make accurate neurological function assessment difficult, such as dementia patients taking cholinesterase inhibitors; 11. Diagnosis of cerebral vasculitis, brain tumor, or traumatic brain injury within the past 3 months; 12. Major organ surgery or biopsy within 30 days; 13. Active bleeding or recent bleeding within 30 days; 14. History of previous intracranial stent implantation; 15. History of severe contrast agent allergy (non-rash allergy); 16. Patients with other contraindications to reperfusion therapy or who refuse reperfusion therapy; 17. Life expectancy less than 180 days; 18. Lactating women or women with positive pregnancy test on admission; 19. Patients who refuse or cannot cooperate with follow-up.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Beijing Tiantan Hospital
Beijing, China
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Other studies related to the condition(s) this trial covers.
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- After stroke, a balloon or a stent? trial tests which rescue opens blocked brain arteries better