Stroke patients may get faster lifesaving care by skipping standard scans
NCT ID NCT07460713
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether sending people with suspected severe stroke directly to the angiography suite (instead of first getting a CT or MRI) can speed up treatment and improve recovery. About 568 adults with stroke symptoms within 6 hours will be randomly assigned to the direct transfer or standard imaging route. The goal is to see if more patients achieve functional independence at 90 days.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- direct transfer to angiography suite (procedure)
- What this could lead to
- If successful, this approach could reduce treatment delays and improve recovery for people with severe stroke caused by a large blocked artery.
- What could go wrong
- This is an early-stage trial with 568 participants, so results may not apply to all stroke patients. The procedure carries risks like bleeding or complications from angiography.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 568 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Mar 2026
An estimate. Start dates often move.
- Expected to finish
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Sep 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age≥18 years old; * Patients presenting with symptoms or signs suggestive of acute large vessel occlusion (LVO) stroke; * Randomization within 6 hours of symptom onset; * Baseline NIHSS score ≥10 points prior to randomization; * Pre-stroke modified Rankin Scale (mRS) score ≤2; * Written informed consent from patients or their legally authorized representatives. Exclusion Criteria: * Refusal of endovascular treatment; * Allergy to contrast agents; * Clinical symptoms or signs suggestive of intracranial hemorrhage (e.g., severe headache, seizures, or signs of increased intracranial pressure); * Transferred patients (e.g., from centers without thrombectomy capability); * Seizure at stroke onset, postictal paralysis, or inability or unwillingness to cooperate due to epilepsy or other neurological or psychiatric disorders; * Clinically unstable conditions requiring urgent life-support treatment; * Other standard contraindications to endovascular treatment; * Any terminal illness such that the patient would not be expected to survive more than 1 year; * Pregnant women, nursing mothers, or women with a positive pregnancy test at admission; * Unlikely to adhere to the trial protocol or follow-up; * Any condition that, in the judgment of the investigator could impose hazards to the patient if study therapy is initiated or affect the participation of the patient in the study; * Participation in other interventional clinical trials within the previous 3 months.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Beijing tiantan hospital
Beijing, Beijing Municipality, 100070, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a checklist and heart monitor stop repeat strokes?
- Heart hole or stroke trigger? global registry tracks who gets closure and what happens next
- Two ways to catch a hidden heart rhythm after stroke
- Blood test may reveal who recovers after a stroke
- Can a smart bracelet and app stop a second stroke?
- Pharmacist and coach team takes aim at blood pressure after stroke