TYPE 2 DIABETES MELLITUS (T2DM)

This study is testing whether a 12-week program using a Fitbit activity tracker and personalized text messages can help people with type 2 diabetes. Researchers want to see if this approach is practical and acceptable for 36 sedentary adults. The goal is to see if this technology…

This study is testing whether a single dose of an investigational drug called ALN-4324 can improve how the body responds to insulin in people with type 2 diabetes. It will involve 40 adult participants who have type 2 diabetes and are already taking a stable dose of metformin. Re…

This study aims to understand how not having reliable access to food affects the health of people living with HIV, especially their risk for heart and metabolic problems like diabetes. Researchers will test a new bilingual program that uses peer support and mobile phone technolog…

This study is testing a new drug called ALN-4324. It first checks the drug's safety in healthy overweight volunteers. Then, it tests if multiple doses can help control blood sugar in people with type 2 diabetes who are also overweight or obese.

This study is investigating whether restricting daily eating to specific time windows can help people with type 2 diabetes, high blood pressure, and obesity better manage their health. Participants will be assigned to either a daytime eating schedule or a nighttime eating schedul…

This study is testing a 12-week exercise program for middle-aged and older adults who have both type 2 diabetes and sarcopenia (age-related muscle loss). The program mixes supervised training, home exercises, and digital support. Researchers want to see if it improves muscle stre…

This study is testing an experimental oral drug called MKP10241 in adults with obesity, some of whom also have type 2 diabetes. The main goals are to see if the drug is safe, how it behaves in the body with and without food, and to look for early signs that it might help with wei…

This study is testing a new program designed to help doctors better screen for and manage chronic kidney disease in people with type 2 diabetes. It will compare a guided management program against basic education to see which leads to more people getting the right medications. Ab…

This study is comparing two approaches for people newly diagnosed with type 2 diabetes who also have excess liver fat. For 12 weeks, one group will receive weekly injections of the medication semaglutide, while the other will follow a strict calorie-restricted diet. Researchers w…

This study is testing whether meals tailored to specific cultural backgrounds can help people with type 2 diabetes manage their blood sugar better. Researchers are comparing blood sugar levels when 30 Asian Indian and Filipino participants eat their regular diet versus specially …

This study is testing a new training program for primary care clinics called ARISE. The goal is to help doctors and nurses better screen for and address 'diabetes distress'—the unique emotional stress of managing the disease—in adults with type 2 diabetes. Researchers want to see…

This study is testing whether a 12-week exercise program can help middle-aged adults with type 2 diabetes improve their muscle strength, physical function, and blood sugar control. Researchers will compare 66 participants who either follow the exercise program plus education or r…

This study has two main goals. First, it aims to find out how common memory and thinking problems are in older adults with type 2 diabetes. Second, it will test a 2-year personalized health program designed to slow down cognitive decline. The program combines medication managemen…

This study is testing if providing free healthy groceries and coaching helps adults with type 2 diabetes and high blood pressure better manage their health. It focuses on people living in Baltimore neighborhoods with limited access to fresh food. Participants are randomly assigne…

This study aims to find the best dental treatment for painful, inflamed tooth nerves in people with type 2 diabetes. Researchers will compare a less invasive procedure that tries to save the living tooth nerve (pulpotomy) against the standard, more extensive root canal treatment.…

This study is testing whether a special probiotic-based toothpaste and mouthwash can help improve gum health and blood sugar control in people who have both type 2 diabetes and gum disease. Forty adult participants will receive standard gum cleaning and then use either the probio…

This study is testing if a wearable continuous glucose monitor (CGM) is easier for pregnant women with type 2 diabetes to use than the standard finger-prick method. It will see if patients are better at tracking their blood sugar with the CGM, which could lead to better health fo…

This study is testing whether replacing regular starchy foods like bread or rice with quinoa can help people with early-stage type 2 diabetes better control their blood sugar and improve their metabolism. Researchers will compare two groups of 60 participants over 14 weeks: one e…

This study is testing a community support program to help adults in Pokhara, Nepal, manage chronic health conditions like high blood pressure, type 2 diabetes, and smoking. It will see if regular home visits from trained local health volunteers, combined with supportive text mess…

This study is testing a combination of diabetes medications to see if it helps control blood sugar levels more steadily throughout the day. It is for adults with type 2 diabetes whose current treatment with metformin and an SGLT-2 inhibitor isn't working well enough. Researchers …

This study is testing if using technology can help people with type 2 diabetes who are starting insulin during a hospital stay manage their condition better when they go home. It will compare a group using a continuous glucose monitor and a smart insulin pen cap that provides rem…

This pilot study is testing a new program to improve diabetes care in two primary health centers in Abuja, Nigeria. It aims to make screening, diagnosis, treatment, and patient education more accessible by training local health workers and providing necessary supplies. The goal i…

This study is creating and testing a Thai version of a questionnaire called PainPREDICT, which will be built into a mobile app. The goal is to help doctors and patients screen for painful nerve damage caused by diabetes more easily and accurately. Researchers will test the app wi…

This study aims to see if simple strategies can encourage people with prediabetes or type 2 diabetes to buy more whole grains instead of refined grains when shopping for groceries online. Researchers will test two approaches: using marketing nudges (like highlighting whole grain …

This study is testing whether a digital health coaching program using smartwatch data can help people improve their lifestyle and prevent chronic diseases. It will enroll 1,700 adults in Singapore who are at risk for or already have conditions like high blood pressure, prediabete…

This study is testing if a personalized diet plan works better than standard healthy eating advice to prevent type 2 diabetes. Researchers will enroll 240 overweight adults and use a computer model to group them by their metabolism and body type. One group will get a diet custom-…

This study is testing whether using a continuous glucose monitor (CGM) helps people with diabetes feel more in control and satisfied with their care after they leave the hospital. Researchers will give 60 adults with type 1 or type 2 diabetes a CGM to use at home for a period aft…

This study aims to learn how young Hispanic/Latinx adults with type 2 diabetes use continuous glucose monitors (CGMs). Researchers will provide 40 participants with CGMs to wear for 30 days and interview them about their experience. The goal is to understand the challenges and be…

This study aims to understand how mental health and quality of life are connected to type 2 diabetes. Researchers will survey 500 adults with diabetes about their well-being, depression, and daily life. The goal is to gather information that can help doctors provide better mental…

This study aims to understand how a person's body weight influences their physical activity, strength, balance, and overall quality of life if they have type 2 diabetes. Researchers will recruit 50 volunteers with type 2 diabetes and measure these factors through interviews, walk…

This study aims to find the best way to get people with type 2 diabetes the recommended screening for chronic kidney disease (CKD). Researchers will enroll 750 adults with diabetes who are overdue for kidney tests. They will compare whether sending a home test kit or a standard l…

This study aims to understand the connection between a person's ability to imagine movements (motor imagery), their awareness of their own body, and their thinking skills (cognition) in people with type 2 diabetes. Researchers will enroll 100 adults with type 2 diabetes to comple…

This study aims to understand how fasting and temporarily stopping the diabetes medication dulaglutide affect how much food and liquid stays in the stomach after a meal. Researchers will use ultrasound scans to measure stomach contents in about 20 adults with type 2 diabetes. The…

This study aims to learn more about patients with type 2 diabetes who are also malnourished or at risk of malnutrition. Researchers will observe 334 adults in Spain who have been prescribed a special high-calorie, high-protein nutritional drink designed for diabetes. Over six mon…