Do steroid shots work as well for carpal tunnel in diabetics?
NCT ID NCT07433257
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study will give a steroid and numbing injection to 60 people with carpal tunnel syndrome, half of whom also have type 2 diabetes. Researchers will track pain, nerve function, and hand strength for 12 weeks to see if the diabetes group recovers as well as those without diabetes. The goal is to understand if this common treatment works similarly for both groups.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- triamcinolone acetonide (a corticosteroid) plus lidocaine (a local anesthetic)
- What this could lead to
- If successful, this study could show that a simple injection works equally well for people with diabetes, helping guide better treatment for this group.
- What could go wrong
- This is a small, observational study with only 60 participants, so results may not apply to everyone. It does not test a new treatment, just compares recovery in two groups.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Mar 2026
- Expected to finish
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Jul 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients who presented to the Physical Medicine and Rehabilitation outpatient clinic with clinical symptoms consistent with carpal tunnel syndrome and were diagnosed with mild-to-moderate carpal tunnel syndrome
- Ages
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18 to 75 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria * Carpal Tunnel Syndrome with Type 2 Diabetes Mellitus Group (Group 1): * Age between 18 and 75 years * Presence of clinical symptoms compatible with carpal tunnel syndrome (e.g., pain, paresthesia, numbness) for at least 3 months * Patients diagnosed with mild-to-moderate carpal tunnel syndrome based on electrophysiological findings * Diagnosis of type 2 diabetes mellitus * Regulated blood glucose levels, defined as hemoglobin A1c (HbA1c) \< 7% * Idiopathic Carpal Tunnel Syndrome Group (Group 2): * Age between 18 and 75 years * Presence of clinical symptoms consistent with carpal tunnel syndrome (e.g., pain, paresthesia, numbness) for at least 3 months * Patients diagnosed with mild-to-moderate carpal tunnel syndrome based on electrophysiological findings * No diagnosis of diabetes mellitus Exclusion Criteria * Severe carpal tunnel syndrome based on electrophysiological findings * Presence of polyneuropathy, cervical radiculopathy, brachial plexopathy, or thoracic outlet syndrome * Uncontrolled blood glucose levels in the diabetic group (hemoglobin A1c ≥ 7%) * Presence of another systemic disease, other than diabetes mellitus, that may cause carpal tunnel syndrome * Presence of a rheumatological disease * History of wrist surgery * Less than 6 months since a local corticosteroid injection for carpal tunnel syndrome * Less than 3 months since completion of a physical therapy program for carpal tunnel syndrome * Infection at the intended injection site * Presence of malignancy * Pregnancy
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Istanbul Haydarpasa Numune Training and Research Hospital
RECRUITINGIstanbul, Istanbul, 34668, Turkey (Türkiye)
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can carpal tunnel surgery restore more than hand function?