TYPE 2 DIABETES MELLITUS (T2DM)

This study tests a new medication called maridebart cafraglutide in 409 adults with type 2 diabetes. The goal is to see if it improves blood sugar levels and helps with weight loss compared to a placebo. Participants must have had diabetes for at least 6 months and be on diet/exe…

This early-phase study tests whether rosemary extract can improve markers of oxidative stress and inflammation in 40 adults with type 2 diabetes. Participants take either rosemary extract or a placebo for 12 weeks. The goal is to see if this natural supplement can support metabol…

This study tests a new medicine called GZR18 in 274 Chinese adults with type 2 diabetes whose blood sugar is not well controlled by diet and exercise alone. The goal is to see if the injection can safely lower blood sugar levels and help with weight loss. Participants will receiv…

This study tests a 12-week telenursing program where nurses teach and support people with type 2 diabetes through video calls. It includes 128 adults in Thailand who have poorly controlled blood sugar. The goal is to see if this approach is practical and helps improve blood sugar…

This study tests a new once-weekly injection called CT-388 in 360 adults who are overweight or obese and have type 2 diabetes. Participants receive either the study drug or a placebo for 48 weeks. The goal is to see if the drug helps with weight loss and improves blood sugar leve…

This study tests a digital tool called DIPAR that sends reminders to adults with type 2 diabetes to get their urine tested for kidney function. The goal is to see if the tool helps more patients get this important yearly check-up. About 200 participants will use the tool through …

This study looks at whether exercise, cognitive training, or both can improve the physical and mental abilities of adults aged 60 and older who have had a stroke and also have high blood pressure or diabetes. About 444 participants from community health centers in five Chinese ci…

This study tests whether a mobile health program using text messages can help people with type 2 diabetes in Nepal better manage their blood sugar. About 154 adults will either receive standard care alone or standard care plus regular text messages for 6 months. The main goal is …

This study compares a new once-weekly injection (GZR102) with a bi-weekly one (GZR18) in 90 adults with type 2 diabetes whose blood sugar is not well controlled on current GLP-1 medications. The goal is to see which schedule works better for lowering blood sugar and weight, while…

This study looks at how the timing of meals and sleep patterns impact blood sugar control, heart disease risk, and weight loss in adults with type 2 diabetes, high blood pressure, or obesity. Researchers will provide nutritional guidance and track changes in weight, blood tests, …

This study aimed to see if a single pill combining two diabetes drugs (SGLT2 inhibitor and thiazolidinedione) works better than taking either drug alone for people with type 2 diabetes already on metformin. The goal was to improve blood sugar control and reduce side effects like …

This study tests a new medicine called GZR18 in about 1,100 Chinese adults with type 2 diabetes whose blood sugar is not well controlled by metformin alone or with other diabetes pills. Participants receive either GZR18 or an active comparator to see which works better at lowerin…

This study tests a program that helps adults with type 2 diabetes use data from wearable glucose and activity monitors to improve their daily self-management. About 80 participants will use a smartphone app to track their health habits and receive personalized feedback. The goal …

This pilot study tests whether diabetes care can be successfully added to two primary health centers in Abuja, Nigeria. Researchers will screen, diagnose, treat, and educate 106 adults with uncomplicated type 2 diabetes. The goal is to see if this approach is practical and effect…

This study follows 50 obese patients (BMI over 32) aged 16-60 who are having weight-loss surgery. Researchers use MRI scans and blood tests before surgery and at 1, 3, and 6 months after to measure fat in the pancreas and check how well the pancreas is working. The goal is to see…

This early-stage study is testing two experimental drugs (L03RD1 and L03RD2) for type 2 diabetes in 48 healthy adults aged 19-55. The goal is to see how the body processes these drugs and check for safety. Participants will receive single doses in a crossover design. This study d…

This study looks at how fasting and temporarily stopping the diabetes drug dulaglutide affect the amount of food and drink left in the stomach after a meal. About 20 adults with type 2 diabetes will have their stomach contents checked using ultrasound. The study lasts about 28 we…

This study looks at whether a common diabetes drug (SGLT2 inhibitor) can help prevent another heart attack or stroke in people with type 2 diabetes who have already had a heart attack. Researchers will compare the health outcomes of 200,000 patients who took either an SGLT2 inhib…