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Study uses MRI to see inside pancreas after Weight-Loss surgery

NCT ID NCT07464223

Knowledge-focused Sponsor: yu li，MD Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study follows 50 obese patients who are having weight-loss surgery (laparoscopic sleeve gastrectomy). Researchers use MRI scans and blood tests before surgery and at 1, 3, and 6 months after to measure changes in pancreatic fat and insulin function. The goal is to see if losing weight helps the pancreas work better and improves type 2 diabetes.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
laparoscopic sleeve gastrectomy (weight-loss surgery)
What this could lead to
If successful, this study could help doctors understand how weight-loss surgery improves metabolic health and guide better post-surgery care.
What could go wrong
This is a small observational study (50 people) with no control group, so results may not apply to everyone. It only measures changes, not tests a new treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 50 people

The number the study aims to enrol. It can still change while the study runs.

Started

Sep 2024

Expected to finish

Apr 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Obese patients aged 16-60 years with BMI \>32 kg/m² undergoing laparoscopic sleeve gastrectomy at Qingdao University Affiliated Hospital. Participants must have preoperative evidence of pancreatic fat infiltration and complete medical records. Both male and female patients are eligible.

Ages

16 to 60 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age between 16 and 60 years * BMI \> 32 kg/m² * Preoperative auxiliary examination supports diagnosis of pancreatic fat infiltration * Willing to undergo pancreatic MRI examination * Previous attempts at other weight loss methods have been ineffective * Complete medical records available * Voluntary signed informed consent * Scheduled to undergo laparoscopic sleeve gastrectomy (LSG) at Qingdao University Affiliated Hospital Exclusion Criteria: * Secondary obesity * Previous major gastrointestinal surgery * Diagnosed gastric or duodenal ulcer * Gastrointestinal diseases associated with malabsorption * Other diseases causing abnormal pancreatic function * BMI \< 32 kg/m² * Poor compliance or self-control, unable to follow dietary guidance after surgery * Unable to complete follow-up visits * Contraindications for MRI examination * Pregnancy or lactation

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Conditions

The condition(s) this trial relates to.

Insulin Resistance Obesity obesity disorder Overweight type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Insulin resistance Obesity & overweight Pancreatic steatosis Type 2 diabetes mellitus (T2DM)

Contacts and locations

Locations

  • Qingdao University Affiliated Hospital

    Qingdao, Shandong, 266003, China

More trials for these conditions

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