RECTAL ADENOCARCINOMA
Clinical trials for RECTAL ADENOCARCINOMA explained in plain language.
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Precision combo slashes rectal cancer treatment side effects?
Disease control Not yet recruitingThis study tests a new approach for people with locally advanced rectal cancer. Instead of standard large-field radiation before surgery, it uses MRI-guided, short-course radiation targeted only at the tumor, combined with immunotherapy and chemotherapy. The goal is to reduce sid…
Matched conditions: RECTAL ADENOCARCINOMA
Phase: PHASE2 • Sponsor: Longhao Li • Aim: Disease control
Last updated May 26, 2026 12:01 UTC
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New combo therapy aims to shrink rectal tumors and save organs
Disease control Not yet recruitingThis study tests a mix of four treatments—immunotherapy, a cancer-killing virus, short-course radiation, and chemotherapy—given before surgery for locally advanced rectal cancer. The goal is to see if this combination can make the cancer disappear completely for at least a year, …
Matched conditions: RECTAL ADENOCARCINOMA
Phase: PHASE2 • Sponsor: Chongqing University Cancer Hospital • Aim: Disease control
Last updated May 26, 2026 12:01 UTC
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New combo attack on tough rectal cancer enters phase 3 trial
Disease control Not yet recruitingThis phase 3 trial tests whether adding immunotherapy and a targeted drug (based on tumor genetics) to standard short-course radiation and chemotherapy can improve outcomes for people with high-risk rectal cancer that is mismatch repair proficient (pMMR/MSS). About 204 adults age…
Matched conditions: RECTAL ADENOCARCINOMA
Phase: PHASE3 • Sponsor: Sixth Affiliated Hospital, Sun Yat-sen University • Aim: Disease control
Last updated May 22, 2026 14:02 UTC
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Blood test may revolutionize rectal cancer care, study hints
Knowledge-focused Not yet recruitingThis study tests whether a sensitive blood test (ctDNA) can help doctors decide the best treatment for people with early-stage rectal cancer. About 200 participants will either have standard treatment or have their treatment guided by the blood test results. The goal is to see if…
Matched conditions: RECTAL ADENOCARCINOMA
Phase: PHASE2 • Sponsor: University of California, Davis • Aim: Knowledge-focused
Last updated May 26, 2026 12:13 UTC
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Who should tell relatives about cancer genes? study tests doctor vs. patient approach
Knowledge-focused Not yet recruitingThis study looks at the best way to inform close relatives (parents, siblings, children) of people newly diagnosed with colorectal cancer about their possible genetic risk. It compares having the patient share the information versus having a healthcare provider do it. The goal is…
Matched conditions: RECTAL ADENOCARCINOMA
Phase: NA • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Knowledge-focused
Last updated May 26, 2026 12:08 UTC
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New camera could speed up cancer checks after rectal surgery
Knowledge-focused Not yet recruitingThis study tests a short camera called a rectoscope to check the lower bowel after rectal tumor or polyp removal. The goal is to see if it can be used in the clinic with a simple enema instead of strong bowel prep, making follow-up exams easier and faster. Thirty patients will ta…
Matched conditions: RECTAL ADENOCARCINOMA
Sponsor: University of Edinburgh • Aim: Knowledge-focused
Last updated May 26, 2026 12:03 UTC
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Can Scope-Based surgery replace the knife for rectal cancer?
Knowledge-focused Not yet recruitingThis study looks back at medical records of 300 adults who had rectal tumors removed between 2015 and 2025. Researchers want to see if newer endoscopic techniques (using a scope through the anus) are as safe and effective as standard abdominal surgery for early-stage rectal cance…
Matched conditions: RECTAL ADENOCARCINOMA
Sponsor: Jagiellonian University • Aim: Knowledge-focused
Last updated May 20, 2026 11:57 UTC
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Hidden cancer clues: are doctors missing key tumor spots?
Knowledge-focused Not yet recruitingThis study looks at whether doctors are properly reporting tumor deposits—small cancer spots near the main tumor—in rectal cancer patients. These deposits can signal a higher risk of cancer returning, but they were often missed in older staging systems. By comparing reports from …
Matched conditions: RECTAL ADENOCARCINOMA
Sponsor: Imperial College London • Aim: Knowledge-focused
Last updated May 20, 2026 11:53 UTC