RECTAL ADENOCARCINOMA
Clinical trials for RECTAL ADENOCARCINOMA explained in plain language.
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New drug duo aims to control stubborn colorectal cancer
Disease control OngoingThis study is testing whether combining two existing drugs, cabozantinib and nivolumab, can help control advanced colorectal cancer that has stopped responding to standard treatments. It will involve about 48 adults whose cancer has spread and is a specific type called microsatel…
Matched conditions: RECTAL ADENOCARCINOMA
Phase: PHASE2 • Sponsor: University of Colorado, Denver • Aim: Disease control
Last updated Apr 04, 2026 04:51 UTC
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Doctors test Real-Time MRI scans to boost rectal cancer treatment
Disease control OngoingThis early-phase study is testing whether using MRI scans to guide and adjust radiation therapy in real time is a practical approach for treating rectal cancer. The goal is to see if this more precise method can help more patients achieve a complete response, meaning no detectabl…
Matched conditions: RECTAL ADENOCARCINOMA
Phase: EARLY_PHASE1 • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Disease control
Last updated Apr 02, 2026 14:57 UTC
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New drug combo tested to shrink rectal tumors before surgery
Disease control OngoingThis early-stage study aims to find the safest dose of the chemotherapy drug TAS-102 when given alongside radiation therapy to patients with stage II or III rectal cancer. The goal is to shrink the tumor before the patient undergoes standard surgery and follow-up chemotherapy. Re…
Matched conditions: RECTAL ADENOCARCINOMA
Phase: PHASE1 • Sponsor: OHSU Knight Cancer Institute • Aim: Disease control
Last updated Apr 01, 2026 14:43 UTC
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Scientists hunt for genetic clues to rising colon cancer in young adults
Knowledge-focused OngoingThis study aims to understand why some people develop colorectal cancer at a young age (18-50) by comparing them to those diagnosed later in life. Researchers are collecting genetic information, medical histories, and lifestyle data from 818 patients and their family members to i…
Matched conditions: RECTAL ADENOCARCINOMA
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Apr 04, 2026 04:51 UTC
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Tracking life after rectal cancer: how surgery affects daily living
Knowledge-focused TerminatedThis study aims to understand how rectal cancer surgery affects patients' quality of life over time. Researchers will follow 430 patients for up to 5 years after their surgery, asking them to complete questionnaires about their daily experiences. The goal is to gather information…
Matched conditions: RECTAL ADENOCARCINOMA
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:28 UTC