RECTAL ADENOCARCINOMA
Clinical trials for RECTAL ADENOCARCINOMA explained in plain language.
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New drug combo shows promise in shrinking rectal tumors before surgery
Disease control OngoingThis early-stage study tests the safety of combining the chemotherapy drug TAS-102 with radiation therapy for people with stage II or III rectal cancer that hasn't been treated yet. The goal is to find the safest dose of TAS-102 to use with radiation before surgery. About 19 adul…
Matched conditions: RECTAL ADENOCARCINOMA
Phase: PHASE1 • Sponsor: OHSU Knight Cancer Institute • Aim: Disease control
Last updated May 26, 2026 12:07 UTC
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Smart radiation: MRI tailors treatment for rectal cancer
Disease control OngoingThis study tests whether using MRI scans during radiation therapy can help doctors adjust the treatment to improve results for people with locally advanced rectal cancer. About 20 participants will receive chemoradiation that is adapted based on MRI images. The goal is to see if …
Matched conditions: RECTAL ADENOCARCINOMA
Phase: EARLY_PHASE1 • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Disease control
Last updated May 26, 2026 12:05 UTC
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New combo therapy aims to stall hard-to-treat colon cancer
Disease control OngoingThis study tests a two-drug combination (cabozantinib and nivolumab) in people with advanced colorectal cancer that is microsatellite stable (MSS) and has stopped responding to standard treatments. The goal is to see if the combination can control the cancer for at least 16 weeks…
Matched conditions: RECTAL ADENOCARCINOMA
Phase: PHASE2 • Sponsor: University of Colorado, Denver • Aim: Disease control
Last updated May 26, 2026 12:04 UTC
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New drug combo shows promise against advanced rectal cancer
Disease control OngoingThis study tests whether adding the experimental drug LY2157299 to standard chemotherapy and radiation can improve outcomes for people with locally advanced rectal cancer. About 50 adults will receive the combination over 8 weeks, and researchers will track tumor response and imm…
Matched conditions: RECTAL ADENOCARCINOMA
Phase: PHASE2 • Sponsor: Providence Health & Services • Aim: Disease control
Last updated May 18, 2026 12:12 UTC
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Scientists hunt for genetic clues to Young-Onset colon cancer
Knowledge-focused OngoingThis study aims to find genetic markers that may increase the risk of developing colorectal cancer at a young age (between 18 and 50). Researchers will compare medical records, lifestyle information, and genetic data from 818 patients and their family members. The goal is to bett…
Matched conditions: RECTAL ADENOCARCINOMA
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated May 26, 2026 13:44 UTC