Rectal adenocarcinoma
Clinical trials for Rectal adenocarcinoma explained in plain language.
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Rearranging the treatment timeline: could a new sequence of chemo and radiation spare rectal cancer patients from major surgery?
Disease control Stopped earlyThis trial is testing whether giving chemotherapy before the standard combination of chemo and radiation for rectal cancer could allow some patients to have a minor surgical procedure instead of a major one. The study enrolls adults with stage T2-T3 rectal cancer. The goal is to …
Matched conditions: RECTAL ADENOCARCINOMA
Sponsor: Henry Ford Health System • Aim: Disease control
Last updated Jul 25, 2026 00:00 UTC
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Rectal cancer: could a 'Watch and Wait' strategy spare patients from major surgery?
Disease control Stopped earlyThis trial is testing whether a 'watchful waiting' approach after chemotherapy and radiation can safely avoid radical surgery in people with a certain type of rectal cancer. Participants receive chemotherapy (FOLFOX) followed by chemo-radiation, and those whose tumors completely …
Matched conditions: RECTAL ADENOCARCINOMA
Sponsor: Henry Ford Health System • Aim: Disease control
Last updated Jul 25, 2026 00:00 UTC
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Pre-Surgery drug cocktail aims to wipe out rectal cancer
Disease control Stopped earlyThis trial investigates whether giving a combination of bevacizumab (a drug that blocks blood vessel growth to tumors) and chemotherapy before surgery can eliminate all signs of cancer in people with stage II or III rectal cancer. Participants receive the treatment before their p…
Matched conditions: RECTAL ADENOCARCINOMA
Phase 2 • Sponsor: University of Southern California • Aim: Disease control
Last updated Jul 03, 2026 00:00 UTC
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New gel aims to stop deadly leaks after bowel surgery
Disease control Stopped earlyThis study tested a new gel called Dehisgel in 20 adults who had colorectal surgery for rectal cancer. The goal was to see if the gel could safely prevent leaks where the bowel was reconnected. The study was stopped early, so results are limited.
Matched conditions: RECTAL ADENOCARCINOMA
Sponsor: Contipro Pharma a.s. • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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New pill for Hard-to-Treat cancers shows early promise in small study
Disease control Stopped earlyThis early-stage study tested a new oral drug, ATX-559, in 17 people with advanced solid tumors that had stopped responding to standard treatments. The main goal was to find a safe dose and check for side effects. The study was terminated early, so results are limited.
Matched conditions: RECTAL ADENOCARCINOMA
Phase 1 • Sponsor: Accent Therapeutics • Aim: Disease control
Last updated Jun 27, 2026 09:08 UTC
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Short radiation course for rectal cancer aims to ease side effects
Symptom relief Stopped earlyThis study tested a short course of targeted radiation (IMRT) given over one week before surgery for rectal cancer. The goal was to see if this approach could reduce side effects like bowel problems and improve quality of life compared to standard longer treatments. Only 2 people…
Matched conditions: RECTAL ADENOCARCINOMA
Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 13:08 UTC