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New pill for Hard-to-Treat cancers shows early promise in small study

NCT ID NCT06625515

First seen Jan 11, 2026 · Last updated Jun 18, 2026 · Updated 30 times

Summary

This early-stage study tested a new oral drug, ATX-559, in 17 people with advanced solid tumors that had stopped responding to standard treatments. The main goal was to find a safe dose and check for side effects. The study was terminated early, so results are limited.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • NEXT Oncology

    San Antonio, Texas, 78229, United States

  • SCRI Oncology Partners

    Nashville, Tennessee, 37203, United States

  • Stephenson Cancer Center at OU Medicine

    Oklahoma City, Oklahoma, 73104, United States

  • The University of Texas MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • University of Colorado Cancer Center - Anschutz Medical Campus,

    Aurora, Colorado, 80045, United States

Conditions

The condition(s) this trial relates to.

breast cancer colon carcinoma colonic neoplasm colorectal cancer endometrial cancer endometrium neoplasm Her2-receptor negative breast cancer metastatic malignant neoplasm Microsatellite Instability neoplasm rectal neoplasm rectum adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.