300 rectal cancer Patients' tissues analyzed to unlock secrets of treatment response
NCT ID NCT07499921
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study will look at tumor samples and health records from 300 people who had surgery for rectal cancer. The goal is to find patterns in the tumor's immune environment that can predict which patients will respond well to chemotherapy or immunotherapy. This could help doctors identify patients who might avoid surgery and preserve their rectum, improving quality of life.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 300 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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May 2026
An estimate. Start dates often move.
- Expected to finish
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May 2033
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Male or female aged 18 or over * Patients who have undergone surgery for rectal cancer since January 1st, 2019 * Histological diagnosis of rectal adenocarcinoma confirmed on a surgical sample Exclusion Criteria: * Not applicable
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Centre Léon Bérard
Lyon, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- New injectable drug tested against Hard-to-Treat solid tumors
- Robotic surgery vs standard approaches: does the platform change cancer outcomes?
- Could a nasal tube replace a temporary ileostomy after rectal cancer surgery?
- Blood test aims to catch Cancer's return earlier
- Blood test guides immunotherapy for hidden cancer cells