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Are doctors missing hidden cancer clues? new study investigates

NCT ID NCT07345273

Knowledge-focused Sponsor: Imperial College London Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether doctors are properly reporting small cancer spots called tumor deposits in people with rectal cancer. These spots can show if the cancer is more aggressive and might need extra treatment like chemo or radiation. Researchers will compare reports from before and after 2018, when new guidelines were introduced, to see if reporting has improved.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 225 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Feb 2026

An estimate. Start dates often move.

Expected to finish

May 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients (\>16 years old) with primary adenocarcinoma of the rectum who have undergone resectional surgery

Ages

16 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Primary adenocarcinoma of the rectum (proven by biopsy) 2. Undergone surgical resection between 01st January 2007 to 31st December 2017 inclusive for the TNM 5 cohort 3. Undergone surgical resection between 01st January 2022 to 31st December 2024 inclusive for the TNM 8 cohort 3\. Staging with MRI reports are available 4. Post-operative pathology report available 5. Patients aged 16 years and over Exclusion Criteria: 1. Synchronous metastatic tumours 2. Under the age of 16 years 3. MRI and/or pathology reports are not available

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Conditions

The condition(s) this trial relates to.

rectal neoplasm rectum adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Rectal adenocarcinoma

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    4 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Basingstoke and North Hampshire Hospital

    Basingstoke, RG24 9NA, United Kingdom

  • Croydon Health Services NHS Trusts

    Croydon, Select Your County, CR7 7YE, United Kingdom

  • Epsom and St Helier University Hospitals NHS Trust

    Surrey Quays, SM5 1AA, United Kingdom

  • London North West University Healthcare NHS Trust

    London, Select Your County, NW10 7NS, United Kingdom

More trials for these conditions

Other studies related to the condition(s) this trial covers.