POST-TRAUMATIC STRESS DISORDER

This study tests whether a trauma-informed program called Strength at Home works better than the usual state-approved program for reducing intimate partner violence. About 800 men who are court-ordered to attend such programs, along with their partners, will take part. Researcher…

This pilot study tests whether a non-invasive brain stimulation technique called rTMS can help reduce alcohol cravings in veterans who also have mild traumatic brain injury (mTBI) and/or post-traumatic stress disorder (PTSD). The study plans to enroll 20 veterans, with half recei…

This study tests whether fluoxetine, a standard antidepressant, can reduce PTSD symptoms in active-duty service members, veterans, and civilians. About 200 participants will receive either the drug or a placebo for 12 weeks, with researchers tracking changes in symptom severity a…

This early-stage study tests whether psilocybin, the active ingredient in magic mushrooms, can safely help adults with chronic PTSD who are already on antidepressants. Twenty participants will receive psilocybin therapy, with some also getting trauma-focused talk therapy. The goa…

This study looks at whether unlicensed professionals can successfully give cognitive behavioral therapy (CBT) to patients in a general hospital. About 250 adults with conditions like anxiety, depression, OCD, or PTSD will take part. The goal is to see if this approach improves ps…

This study tests a therapy called Deep Brain Reorienting (DBR) for people with PTSD. 234 adults will be randomly assigned to receive DBR or join a waitlist. Researchers will measure changes in PTSD symptoms using a standard scale to see if DBR helps.

This study tests whether a non-invasive brain stimulation technique called TMS can help lower blood pressure and reduce PTSD symptoms in women aged 18-44 who have both conditions. Thirty participants will receive TMS and have their blood pressure monitored for 24 hours. The goal …

This study tests an experimental drug (SLS-002) for Post Traumatic Stress Disorder (PTSD) in 200 active-duty service members, veterans, and civilians. Participants receive either the drug or a placebo via nasal spray twice a week for 8 weeks, then once a week for 4 more weeks. Th…

This study tests whether a stellate ganglion block—an injection of numbing medicine near nerves in the neck—can reduce PTSD symptoms and related brain activity. About 79 adults with chronic PTSD will receive either the real injection or a placebo (saline). Researchers will measur…

This study compares a new short therapy for PTSD to the usual longer treatments. About 82 adults with PTSD or subthreshold PTSD will receive either the brief intervention or standard care. Researchers will measure changes in PTSD symptoms and quality of life to see if the shorter…

This study tests a short therapy called Brief Prolonged Exposure (Brief PE) to see if it can reduce post-traumatic stress in people who have had a spinal cord injury. About 200 adults in inpatient rehab will either get the therapy or standard care. The goal is to ease PTSD sympto…

This study looks at whether a brain training method called neurofeedback can help new mothers who have experienced childhood trauma feel better emotionally. Twenty moms between 3 and 24 months after giving birth will try the training and report on their mood, stress, and parentin…

This study aimed to see if propranolol, a blood pressure medicine, could reduce PTSD symptoms in teenagers by interfering with the way traumatic memories are re-stored in the brain. It planned to enroll 12- to 18-year-olds with PTSD for at least three months. However, the study w…

This study tests whether a mobile neurofeedback program can help new mothers who have experienced trauma feel less stressed, anxious, and depressed. About 40 mothers with PTSD symptoms and babies aged 3-9 months will use the app for 12 weeks. Researchers will check if it improves…

This study tests whether a stellate ganglion block—a numbing injection near the neck—can safely and quickly reduce PTSD symptoms in veterans. About 410 veterans with chronic PTSD who have tried other treatments will receive either the real injection or a sham (fake) one. Research…

This study tests a web-based program called webSTAIR for people with PTSD who are waiting for treatment. The goal is to see if it's easy to use, helpful, and can reduce PTSD symptoms. About 70 adults from a Boston clinic will take part, using a computer or phone to learn skills f…

This study explores whether artificial intelligence (AI) can analyze a person's speech to help diagnose mental health conditions like depression, anxiety, ADHD, and autism. Researchers will collect speech samples from 500 people aged 16-60 who are being evaluated for mental healt…

This study was designed to see if a program called PCIP could help teens with PTSD in primary care settings, and whether it could be delivered via telehealth. It planned to enroll 44 teens and their caregivers to measure changes in PTSD knowledge, symptoms, and coping skills. How…