POST-TRAUMATIC STRESS DISORDER

This study is testing whether a single dose of MDMA (commonly known as ecstasy) given during intensive therapy sessions can help people with PTSD more than therapy alone. Researchers will enroll 200 adults with PTSD who will receive either MDMA or a placebo during their second th…

This study aims to understand how a single dose of psilocybin (the active compound in 'magic mushrooms'), given with different types of therapy, might help people with PTSD. It will enroll 30 adults with moderate to severe PTSD to see how their brain activity and symptoms change.…

This study is testing whether a quick-dissolve film called BXCL501, given in the emergency room after a car accident, can reduce immediate stress reactions and prevent long-term PTSD symptoms. Researchers will enroll 100 adults who come to the ER within 24 hours of a car crash an…

This study aims to see if a medication called vilazodone is safe and can help control symptoms of Post-Traumatic Stress Disorder (PTSD). It will involve 200 active-duty service members and veterans. Participants will be randomly assigned to receive either the real medication or a…

This study is testing whether combining a single dose of psilocybin (a compound found in 'magic mushrooms') with an intensive week of therapy can help people with chronic, treatment-resistant PTSD. Fifteen participants will receive the combined treatment and be followed for 12 we…

This study aims to test the safety and effectiveness of a new nasal spray medication called SLS-002 for treating Post-Traumatic Stress Disorder (PTSD). It will involve 200 active-duty service members and veterans who will receive either the drug or a placebo for 12 weeks. The mai…

This study is testing whether therapy sessions combined with the drug MDMA can help military veterans who struggle with both post-traumatic stress disorder (PTSD) and alcohol use disorder. Researchers will compare the full MDMA-assisted therapy to a similar therapy with a very lo…

This small pilot study is testing if a brief, video-based sleep therapy can prevent PTSD and depression in people at high risk after a car accident. Researchers will enroll 20 adults who go to the emergency room after a crash and are sent home. The goal is to see if this approach…

This study aims to see if using cannabis (marijuana) during a specific therapy helps veterans with PTSD feel less distress. Researchers will give either real cannabis or a placebo to 280 veterans right before their therapy sessions. They will measure PTSD symptoms, anxiety, and b…

This study is testing whether a single dose of psilocybin, taken in a controlled therapy session, can help reduce PTSD symptoms in women who have experienced sexual assault. It will involve 35 participants and closely monitor safety, side effects, and changes in PTSD, anxiety, an…

This study aims to see if specific cannabis compounds (THC, CBD, or a mix) can help veterans struggling with PTSD and suicidal thoughts. 500 veterans will be randomly assigned to smoke one of four types of cannabis or a placebo daily for 12 weeks. Researchers will track changes i…

This study is testing a mobile app called 'Along With Me' to see if it can help parents who have recently experienced a miscarriage, stillbirth, or infant death. The app provides lessons and skills to help manage grief, with the goal of reducing symptoms of trauma and suicidal th…

This study is testing whether a body-focused therapy called SMART can help adults with Post-Traumatic Stress Disorder (PTSD). SMART uses movement, touch, and balance exercises to help people feel more connected to their bodies and surroundings. Researchers will enroll 80 adults t…

This study is testing a new therapy designed to help veterans with PTSD and alcohol misuse improve their romantic relationships. The therapy focuses on managing difficult emotions and building healthier relationship skills. It will be piloted with 29 veterans who are experiencing…

This study is testing whether a program of warm water therapy can help veterans with PTSD. Fifty veterans will receive 16 weeks of individual therapy in a warm pool, followed by 16 weeks of group water exercise. The goal is to see if this approach is practical and helps reduce PT…

This study is testing whether MDMA-assisted therapy can safely reduce symptoms of post-traumatic stress in healthcare workers who experienced trauma during COVID-19 frontline work. It will involve 30 participants who live near New York City and will receive therapy sessions combi…

This study aims to understand why young women with PTSD have a higher risk of heart disease later in life. Researchers will test if drinking beetroot juice can improve blood vessel function in 30 women aged 18-40 who have experienced trauma, with or without PTSD. The goal is to g…