PAIN, CHRONIC

This study tested a 12-month program where nurses provided phone-based support to 805 adults with depression and possible opioid use disorder. Participants were randomly assigned to receive the nurse care program or usual care. The goal was to see if nurse support could improve t…

This study tested if an app that teaches better sleep habits could help people with chronic pain and insomnia during a 4-week rehab program. 105 adults took part. The goal was to see if the app improved sleep more than rehab alone.

This study tested a procedure called cooled radiofrequency to treat chronic knee pain from osteoarthritis. It compared two sets of nerve targets to see which provides better pain relief and improves knee function. Ten adults with moderate to severe knee pain participated, and res…

This study tested two treatments for chronic heel pain caused by heel spurs: posterior tibial nerve stimulation (a gentle nerve-zapping technique) and extracorporeal shock wave therapy (sound waves). 100 adults aged 18-65 took part. The goal was to see which method better reduces…

This study tested a new online program that teaches mindfulness and coping skills to people recovering from surgery. The program is completely self-guided, meaning no therapist is needed. Researchers wanted to see if people would find it useful and easy to use compared to a works…

This study tested a one-day educational workshop for adults with chronic non-cancer pain who take high doses of opioids. The workshop, led by a team of doctors, pharmacists, and psychologists, taught about opioid risks and a pain management technique called Acceptance and Commitm…

This study tested two methods of pain control after hip replacement surgery in 60 adults. One group received a continuous nerve block near the spine (erector spinae plane block), while the other received standard epidural pain relief. Researchers measured pain levels, opioid use,…

This study looked at whether self-monitoring physical activity and percussive massage therapy can help reduce chronic pain in women aged 65 and older. 108 participants tracked their steps and massage use to see which approach works best. The goal was to find simple, practical way…

This study tested two programs for adults with long-term (chronic) low back pain that has no clear cause. Both programs included exercise, behavior change, education, and mindfulness; one also added functional resistance training. The goal was to see if these approaches could red…

This study tracked 298 people with chronic pain who received radiofrequency ablation, a procedure that uses heat to target pain nerves. The goal was to see how much their pain improved in the real world. Participants rated their overall change using a standard scale, from 'very m…

This study looked at whether taking an oral muscle relaxant (tizanidine) before spinal anesthesia can improve pain control and reduce the need for extra painkillers after lower limb surgery. 64 adults scheduled for elective leg surgery took part. The goal was to see if the combin…

This study tested whether teaching patients about pain before surgery (called pain neuroscience education) could lower their anxiety, stress, and pain after a total abdominal hysterectomy. 62 adults having this surgery took part. The goal was to see if this simple education sessi…

This study looked at whether follow-up appointments by phone or video (telemedicine) can reduce pain-related disability in adults with cancer pain. Researchers compared 193 patients who either came to the clinic or used telemedicine. The goal was to see if telemedicine could impr…

This study tested a toolkit called Pain at Work (PAW) to help employees with chronic pain manage their condition on the job. Around 380 adults from workplaces in England took part, with some using the toolkit plus support calls and others receiving usual care. The goal was to see…

This study looked at whether a small plug placed in the veins (endovascular plug embolization) can reduce long-term pelvic pain in women with Pelvic Congestion Syndrome. 44 women took part. The goal was to see how quickly pain improved after the procedure. This is a minimally inv…

This study looked at whether cognitive behavioral therapy (CBT) can help people who had surgery for a broken bone feel less pain over the next year. Over 1,000 adults took part, some getting CBT and others usual care. The goal was to see if CBT lowers the chance of developing lon…

This study tested a non-drug treatment called myoActivation for chronic pain in 41 people from marginalized communities. The treatment involves a structured assessment and hands-on therapy to reduce pain and improve daily life. Researchers measured pain levels, function, and qual…

This study tested whether taking over-the-counter ibuprofen or doing specific nerve stretches (called neural mobilization) can reduce pain and improve hand function in people with carpal tunnel syndrome. 123 adults with confirmed carpal tunnel were assigned to one of three groups…

This study looked at 201 adults with chronic back pain who received a type of steroid injection for their pain. Researchers compared those who got sedation (medicine to relax) during the procedure to those who did not. The goal was to see if sedation changed how satisfied patient…

This study tested whether remote tai chi and wellness programs are practical for veterans with PTSD and chronic pain. 42 veterans participated in a 12-week program delivered via video. The goal was to see if veterans were satisfied and would stick with the program, to inform a fu…

This study measured how often hospitalized patients with cirrhosis experience pain. Researchers surveyed 30 adults at one French hospital, asking about pain presence, location, and intensity. The goal was to fill a gap in knowledge, since no French studies had looked at this befo…

This study used special brain scans to look for inflammation in the brains and spines of 60 people with chronic low back pain. Researchers also tested whether a short course of the antibiotic minocycline could reduce that inflammation and ease pain. The goal was to better underst…

This study tested a French version of a questionnaire that measures how people with chronic pain think about their condition. Researchers compared it to a standard pain confidence survey in 80 French-speaking adults with chronic pain. The goal was to see if the new scale provides…

This study looked at 92 people with chronic neck pain to see if a measure of blood flow in the fingers (called perfusion index) could predict how well a nerve block treatment would work. Researchers measured pain levels and disability before and after the procedure. The goal was …

This study looked at whether a person's genes can help choose the best treatment for muscle pain. Researchers tested 80 people with myofascial pain using low-level laser, ultrasound, and prolotherapy. They collected blood and urine samples to find genetic markers that predict whi…

This study worked with 100 torture survivors to better diagnose chronic pain. Researchers tested if adding a simple pain questionnaire could catch pain that standard methods miss. They also interviewed survivors about pain treatments and tested if a digital program could help tra…