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Brain scans reveal hidden inflammation in chronic back pain sufferers

NCT ID NCT03106740

First seen Feb 17, 2026 · Last updated Jun 18, 2026 · Updated 22 times

Summary

This study used special brain scans to look for signs of inflammation in the brains and spinal cords of 60 people with chronic low back pain. Researchers also tested whether a short course of the antibiotic minocycline could reduce both inflammation and pain. The goal was to better understand the role of brain inflammation in chronic pain and explore a potential new treatment approach.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Massachusetts General Hospital

    Charlestown, Massachusetts, 02129, United States

Conditions

The condition(s) this trial relates to.

Back Pain Chronic Pain chronic pain syndrome cyclopia sequence Low Back Pain Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.