Brain scans reveal hidden inflammation in chronic back pain sufferers

NCT ID NCT03106740

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study used special brain scans to look for signs of inflammation in the brains and spinal cords of 60 people with chronic low back pain. Researchers also tested whether a short course of the antibiotic minocycline could reduce both inflammation and pain. The goal was to better understand the role of brain inflammation in chronic pain and explore a potential new treatment approach.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for BACK ACHE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Back Pain Chronic Pain chronic pain syndrome cyclopia sequence Low Back Pain Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Massachusetts General Hospital

    Charlestown, Massachusetts, 02129, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.