OLDER ADULTS
Clinical trials for OLDER ADULTS explained in plain language.
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Fat loss may supercharge exercise benefits for obese seniors
Disease control CompletedThis study looked at whether losing fat through a controlled diet helps obese older adults get more out of exercise. 180 sedentary seniors with a BMI of 30-35 took part. Researchers measured improvements in heart fitness and walking endurance to see if combining calorie restricti…
Matched conditions: OLDER ADULTS
Phase: NA • Sponsor: Wake Forest University Health Sciences • Aim: Disease control
Last updated May 26, 2026 03:13 UTC
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New tech tool helps seniors with diabetes avoid dangerous low blood sugar
Disease control CompletedThis study tested whether a continuous glucose monitor (CGM) combined with a diabetes management platform (DMP) can help older adults (65+) with type 1 diabetes reduce low blood sugar episodes. The DMP automatically sends glucose and insulin data to a system that gives dose adjus…
Matched conditions: OLDER ADULTS
Phase: NA • Sponsor: Joslin Diabetes Center • Aim: Disease control
Last updated May 26, 2026 03:07 UTC
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Walking while hospitalized: new program aims to keep seniors on their feet
Disease control CompletedThis study tested a program called MOVIN that encourages older adults (65+) to walk more while in the hospital. The goal was to prevent loss of function and reduce hospital readmissions. Researchers measured walking speed, daily living skills, and how far patients could move arou…
Matched conditions: OLDER ADULTS
Phase: NA • Sponsor: University of Wisconsin, Madison • Aim: Disease control
Last updated May 26, 2026 03:06 UTC
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Warm calls cut loneliness in seniors, study finds
Symptom relief CompletedThis study tested whether a program of friendly, supportive phone calls (called BE WITH) could help older adults feel less lonely, depressed, and isolated. Over 670 adults aged 55 and older who received meal services took part. Some received weekly calls for 8 weeks, while others…
Matched conditions: OLDER ADULTS
Phase: NA • Sponsor: University of Florida • Aim: Symptom relief
Last updated May 26, 2026 03:18 UTC
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Virtual forest bathing boosts Seniors' spirits
Symptom relief CompletedThis study tested whether watching nature scenes through a virtual reality headset can improve mood, reduce anxiety, and sharpen thinking in older adults who have trouble getting outdoors. Thirty adults aged 60 to 90 took part. The goal was to see if this simple, low-cost approac…
Matched conditions: OLDER ADULTS
Phase: NA • Sponsor: Universitat Internacional de Catalunya • Aim: Symptom relief
Last updated May 26, 2026 03:18 UTC
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Art program lifts depression and age stigma in seniors, study finds
Symptom relief CompletedThis study tested whether a cultural arts program could reduce depressive symptoms and age-related self-stigma in older adults. 63 people aged 60 and older who were at risk for depression took part. The program involved creative arts activities, and results were compared to usual…
Matched conditions: OLDER ADULTS
Phase: NA • Sponsor: The Hong Kong Polytechnic University • Aim: Symptom relief
Last updated May 26, 2026 03:14 UTC
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New program eases depression and anxiety in seniors undergoing hip or knee replacement
Symptom relief CompletedThis study tested a program that combines talk therapy (behavioral activation) with medication adjustments to reduce depression and anxiety in adults aged 60 and older having hip or knee replacement surgery. 116 participants were split into two groups: one received the program pl…
Matched conditions: OLDER ADULTS
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Symptom relief
Last updated May 26, 2026 03:11 UTC
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Beef vs. veggies: which diet fights muscle fatigue in seniors?
Symptom relief CompletedThis study looked at whether eating beef can reduce muscle fatigue in older adults compared to a vegetarian diet. Twenty-four adults aged 60-85 ate either a beef-based or vegetarian diet for 8 weeks, then switched after a break. Researchers measured muscle strength, walking dista…
Matched conditions: OLDER ADULTS
Phase: NA • Sponsor: Indiana University • Aim: Symptom relief
Last updated May 26, 2026 03:10 UTC
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New approach eases anxiety and depression in older cancer surgery patients
Symptom relief CompletedThis study tested a combination of behavioral activation (a type of counseling that encourages positive activities) and medication optimization (adjusting current medicines) to reduce anxiety and depression in adults aged 60 and older undergoing surgery for cancer. 105 participan…
Matched conditions: OLDER ADULTS
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Symptom relief
Last updated May 26, 2026 03:05 UTC
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Simple exercise program boosts brain and body in seniors
Symptom relief CompletedThis study looked at whether a 12-week exercise program (twice a week, 45-60 minutes per session) could help older adults age 65+ become less frail, improve memory and thinking, and sleep better. 110 participants were split into an exercise group and a no-exercise group. The prog…
Matched conditions: OLDER ADULTS
Phase: NA • Sponsor: Neslihan Lok • Aim: Symptom relief
Last updated May 22, 2026 14:03 UTC
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Heart surgery patients get mental health boost from simple talk-and-meds program
Symptom relief CompletedThis study tested a program that combines counseling (behavioral activation) with medication adjustments to reduce depression and anxiety in older adults (age 60+) having heart surgery. 105 participants were split into two groups: one received the program, the other got usual car…
Matched conditions: OLDER ADULTS
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Symptom relief
Last updated May 22, 2026 14:02 UTC
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12-Week fitness boost shows promise for seniors with mobility issues
Symptom relief CompletedThis small pilot study tested a 12-week high-intensity functional training program for adults aged 60 and older who have a long-term mobility disability but can still walk. The goal was to see if the program is feasible and can improve walking speed, endurance, balance, and leg s…
Matched conditions: OLDER ADULTS
Phase: NA • Sponsor: University of Kansas • Aim: Symptom relief
Last updated May 18, 2026 12:11 UTC
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Brain training boosts thinking in older HIV patients
Symptom relief CompletedThis study tested whether 20 hours of executive function training could improve thinking skills and reduce mental ups and downs in adults over 40 with HIV-related cognitive problems. 119 participants were split into a training group and a no-contact control group. The goal was to…
Matched conditions: OLDER ADULTS
Phase: PHASE2 • Sponsor: University of Alabama at Birmingham • Aim: Symptom relief
Last updated May 18, 2026 12:08 UTC
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Online workouts boost strength in seniors with prediabetes
Symptom relief CompletedThis study looked at whether a live, online strength training program called Vivo is practical and helpful for older adults with prediabetes. Twenty-eight sedentary adults aged 60 and older took part in 12 weeks of supervised workouts from home. The results showed good attendance…
Matched conditions: OLDER ADULTS
Phase: NA • Sponsor: Eric Levian • Aim: Symptom relief
Last updated May 13, 2026 16:03 UTC
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Pilot study tests combo of lifestyle, meds, and supplements for healthier aging
Knowledge-focused CompletedThis pilot study explored whether combining lifestyle changes, risk factor management, medications, and supplements could improve motor, cognitive, and immune function in aging adults. 23 sedentary adults aged 50-70 participated. The main goal was to see if the program was feasib…
Matched conditions: OLDER ADULTS
Phase: PHASE2 • Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated May 26, 2026 03:17 UTC
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Study reveals surprising links between exercise and happiness in seniors
Knowledge-focused CompletedThis study looked at how physical activity, life satisfaction, and taking medicine correctly are related in older adults (65+) with chronic conditions like high blood pressure or diabetes. Researchers measured these factors using simple questionnaires in 82 Turkish seniors. The g…
Matched conditions: OLDER ADULTS
Sponsor: Bezmialem Vakif University • Aim: Knowledge-focused
Last updated May 26, 2026 03:13 UTC
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Pill or IV? new study tests safer sedation for Seniors' eye surgery
Knowledge-focused CompletedThis study tested whether giving older adults a pill instead of IV sedation before cataract surgery is feasible and safe. Twenty participants aged 65 and older were randomly assigned to receive either a sedative pill or IV sedation. The goal was to see how well their thinking and…
Matched conditions: OLDER ADULTS
Phase: PHASE4 • Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated May 26, 2026 03:10 UTC
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Blood pressure pills may change brain blood flow in seniors
Knowledge-focused CompletedThis study looked at how blood pressure medications affect brain blood flow and thinking skills in older adults with high blood pressure. Researchers gave 27 participants either a drug or a placebo for 1-2 weeks and measured brain blood flow, nerve activity, and cognitive perform…
Matched conditions: OLDER ADULTS
Phase: EARLY_PHASE1 • Sponsor: University of Texas Southwestern Medical Center • Aim: Knowledge-focused
Last updated May 26, 2026 03:06 UTC
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Walking program shows promise for Seniors' health
Knowledge-focused CompletedThis study tested a program to help older adults (65+) in Jiazhou, China walk more and feel better. 350 participants used strategies like setting goals and adapting to challenges. The goal was to see if this approach increases weekly walking minutes and improves well-being.
Matched conditions: OLDER ADULTS
Phase: NA • Sponsor: Ling Yang • Aim: Knowledge-focused
Last updated May 26, 2026 03:05 UTC
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Game on against oral cancer: app boosts Seniors' health knowledge
Knowledge-focused CompletedThis study tested whether a mobile app with educational videos and serious games could improve knowledge about oral cancer and oral hygiene in adults aged 60 and older. 62 participants used either a version with videos and games or a version with videos only for 4 weeks. The goal…
Matched conditions: OLDER ADULTS
Phase: NA • Sponsor: University of Chile • Aim: Knowledge-focused
Last updated May 22, 2026 14:02 UTC
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Breathing trouble linked to weaker bodies in seniors
Knowledge-focused CompletedThis study looked at 120 older adults (65+) to see if dysfunctional breathing—abnormal breathing patterns without a clear medical cause—affects physical fitness. Participants completed breathing questionnaires and fitness tests like standing from a chair, walking, and stretching.…
Matched conditions: OLDER ADULTS
Sponsor: Istinye University • Aim: Knowledge-focused
Last updated May 18, 2026 12:03 UTC
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Tiny study asks: does MBT work for Over-60s?
Knowledge-focused CompletedThis study looked at whether Mentalization-Based Therapy (MBT) helps people aged 60 and older who struggle in relationships. Three participants received MBT, and researchers used interviews and questionnaires to see if it improved their mental health and ability to understand oth…
Matched conditions: OLDER ADULTS
Sponsor: University of Nottingham • Aim: Knowledge-focused
Last updated May 18, 2026 12:00 UTC