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Virtual brain training shows promise for pain and memory in seniors

NCT ID NCT05373745

First seen Nov 24, 2025 · Last updated Jun 19, 2026 · Updated 24 times

Summary

This study tested two virtual, 8-week programs (Active Brains 1 and 2) in 267 older adults with chronic pain and early cognitive decline. Both programs taught skills like relaxation, cognitive training, and positive psychology to help manage symptoms. Researchers measured changes in physical function, step count, and walking ability, and followed participants for 6 months to see if improvements lasted.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

behavioral intervention (Active Brains 1 and Active Brains 2 programs)

What this could lead to

If successful, these programs could offer a practical, non-drug way for older adults to better manage chronic pain and early memory issues at home.

What could go wrong

This is a completed study comparing two behavioral programs, not a test of a new drug or cure. Results may show only modest benefits, and what works in a study may not work for everyone in daily life.

Conditions

The condition(s) this trial relates to.

Chronic Pain chronic pain syndrome Cognitive Dysfunction Motor Activity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.