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Beef vs. veggies: which diet fights muscle fatigue in seniors?

NCT ID NCT05860088

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether eating beef daily for 8 weeks reduces muscle fatigue in adults aged 60-85 compared to a vegetarian diet. Twenty-four participants ate both diets in a crossover design, with tests like sit-to-stand and walking. The goal was to see if beef's natural beta-alanine and carnosine improve muscle function and fatigue.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

24 people

The number who actually took part.

Started

Jul 2023

Finished

Nov 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

60 to 85 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria * Ages 60-85 years * Ability to eat study diet meals for a total of 16 weeks * Ability to perform sit-to-stand chair and 6-minute walking tests based on results from PAR-Q questionnaire * Ability to provide fasted blood samples * Access to transportation * Willing to abstain from alcohol consumption and/or use illicit drug use for each 8-week intervention period * Ability to consent to participating in this study * English-speaking * Body mass index between 18.5 (normal) and 39.9 (obese) kg/m2 * Minimum total body weight of 110 pounds * Non-anemia hemoglobin values: Females - \>12.0 grams/dL; Men - \>13.0 grams/dL * Able to ambulate without assistance * Physician's clearance for study participation (required prior to baseline testing) Exclusion Criteria * Inability or refusal to sign the informed consent * Significant orthopedic limitations or other contraindications to exercise * Inability or refusal to perform muscle fatigue tests * Has dietary restrictions that prevent to consumption of beef, soy and/or wheat * Has liver or kidney complications * Live or work \>25 miles from Bloomington study site or does not have transportation to the study site * Anticipate elective surgery during the study period * Diagnosis of progressive neurological disorders, musculoskeletal disorders, osteoarthritis, rheumatoid arthritis * Fracture or serious injury in the last 6 months * Stroke, revascularization, deep vein thrombosis, or pulmonary embolism in the past 12 months * Severe cardiovascular disease, uncontrolled systemic hypertension, chronic pulmonary disease * Plan to move residence or travel out of the local area during the study period * Current use of anti-coagulants (e.g. Coumadin or Warfarin) * Current use of prescription medications that affect heart rate or blood vessel dilation * Psychological or social characteristics that would interfere with their ability to fully participate in the study

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Conditions

The condition(s) this trial relates to.

Fatigue Muscle Weakness

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Indiana University Bloomington

    Bloomington, Indiana, 47405, United States

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Other studies related to the condition(s) this trial covers.