INFLUENZA

This study tested a new seasonal flu vaccine made using a different manufacturing method (Vero cells) to see if it was as effective and safe as a standard egg-based flu shot. Over 3,200 adults aged 50 and older received one injection and were monitored for their immune response a…

This study tested a new four-strain flu vaccine in very young children to see how safe it is and how well it triggers a protective immune response. Over 2,700 healthy children aged 6 to 35 months received two doses of either the new vaccine or a control vaccine. Researchers close…

This large study tested whether a new seasonal flu vaccine, made using a different manufacturing method (Vero cells), could prevent people from getting the flu. Over 7,000 participants received either the vaccine or a placebo shot and were monitored for six months to see if they …

This study tested whether a high-dose flu vaccine works better than the standard-dose vaccine for people aged 50 to 64. About 1,180 participants received one of the two shots, and researchers measured their immune response and tracked side effects for about six months. The goal w…

This early-stage study tested a new mRNA-based flu vaccine in healthy adults to see if it's safe and triggers a good immune response. Researchers gave 50 volunteers different doses of the experimental vaccine or a standard flu shot for comparison. The main goal was to check for s…

This study tested new mRNA vaccines designed to protect against both influenza (flu) and COVID-19. Researchers gave healthy adults a single shot containing either a flu vaccine, a COVID-19 vaccine, or a mix of both to see how safe they were and how well they triggered an immune r…

This study tested a single vaccine, called mRNA-1083, designed to protect against both seasonal influenza and COVID-19. It involved 932 adults aged 50 to 65 to check the vaccine's safety and how well it triggers an immune response. The goal is to see if one injection can simplify…

This study tested an experimental flu vaccine that contains an extra H3 influenza strain, in addition to the standard recommended strains. It involved 400 healthy adults in two age groups (18-49 and 60+) to check if the vaccine is safe and if it triggers a good immune response. T…

This study tested a new vaccine, mRNA-1083, designed to protect against both seasonal flu and COVID-19 with a single shot. It involved 1,320 healthy adults aged 18 to 65 to see how well their immune systems responded and to check for side effects. The goal was to see if this comb…

This study tested a new mRNA vaccine designed to protect against both seasonal influenza and COVID-19 in a single shot. It involved over 1,700 healthy adults and aimed to find the safest and most effective dose. The main goals were to check for side effects and measure how well t…

This study tested a new vaccine designed to protect against H7N9 influenza, a type of bird flu. Researchers compared two different strengths of the vaccine mixed with an immune-boosting ingredient (MF59) to the vaccine alone in 581 healthy adults. The main goal was to see which f…

This study tested a new flu vaccine designed to protect against four strains of influenza, comparing it to standard vaccines that protect against three strains. It involved over 7,000 participants in China, from infants as young as 6 months to adults over 65. The main goals were …

This early-stage study tested the safety and immune response of an experimental flu vaccine called FluMos-v2. The vaccine is designed to protect against six different flu strains, potentially offering broader coverage than current shots. Thirty healthy adults received two doses a…

This study tested a new Moderna vaccine designed to protect against both COVID-19 and seasonal influenza with a single injection. It involved over 2,400 healthy adults aged 50 and older in Asia. The main goal was to see how well the body's immune system responded to the combined …

This study tested the safety and immune response of a new mRNA vaccine designed to protect against pandemic influenza strains. Healthy adults received either the experimental vaccine, a standard flu shot, or a placebo. Researchers monitored participants for over a year to see how…

This study tested if a seasonal flu vaccine made with an updated manufacturing process works as well as the old process and a standard licensed flu shot. It involved nearly 2,000 healthy adults. The main goals were to see if the new process produced a similar immune response, was…

This study tested a new flu vaccine made with mRNA technology, similar to Moderna's COVID-19 vaccine. It involved 172 healthy adults and compared the new vaccine's safety and ability to trigger an immune response against standard flu shots. The main goal was to see if the mRNA va…

This study tested whether adding special immune-boosting ingredients, called adjuvants, to two already-approved seasonal flu vaccines would improve their safety and effectiveness. It involved 241 healthy adults aged 18-45. Researchers compared the standard vaccines to versions mi…

This study tested experimental vaccines designed to protect against specific strains of bird flu (H5N1 and H5N8). Researchers gave 1,380 healthy adults two shots of different vaccine formulas to see which ones were safest and triggered the strongest immune response. The main goal…

This study tested a specific H1N1 flu vaccine in pregnant women to see if it safely triggered a protective immune response. It involved about 110 women who were between 22 and 32 weeks pregnant. Researchers gave two vaccine doses and monitored the women's health and immune system…

This early-stage study explored a new vaccination strategy aimed at creating broader protection against multiple flu strains, potentially moving toward a 'universal' flu vaccine. Researchers tested an H5N1 flu shot in 32 healthy adults, comparing those who had received previous e…

This large, completed Phase 3 trial tested a new single vaccine designed to protect against both COVID-19 and seasonal influenza. Nearly 9,000 healthy adults received either the combined shot or separate standard vaccines to compare safety and immune response. The goal is to see …

This small pilot study tested whether using a blood marker called MxA to guide when to stop antiviral treatment could improve outcomes for adults with flu or COVID-19. Researchers compared this new approach to standard care to see if it reduced the chance of the infection coming …

This study tested a new diagnostic tool called the VitaSIRO solo™ assay to see how well it detects COVID-19, influenza (flu), and RSV in people with symptoms. Researchers enrolled over 1,200 participants who showed signs of a respiratory infection and collected nasal swabs from t…

This study tested a new long-acting drug called CD388 to see if it could prevent people from getting the flu. Over 5,000 healthy adults received either one of three doses of the drug or a placebo shot. Researchers measured how many people got lab-confirmed flu and monitored safet…

This large study aimed to find out if a high-dose flu vaccine works better than the standard-dose vaccine at preventing serious illness in adults aged 65 and older. Over 330,000 participants were randomly assigned to receive one of the two vaccines. Researchers used health record…

This study tested a community-designed program to see if it could increase COVID-19 and flu vaccination rates in underserved populations in East London. Nearly 6,000 adults from minority ethnic, low-income, or migrant backgrounds participated. The program used text messages and e…

This study tested whether sending different types of digital reminder letters through Denmark's official government system could encourage more adults with chronic health conditions to get their annual flu vaccine. Over 300,000 participants aged 18-64 with conditions like diabete…

This large analysis combined data from two major trials to see if a high-dose flu vaccine works better than the standard dose at preventing severe illness in older adults. It involved over 466,000 participants aged 65 and older from Denmark and Spain. The goal was to get clearer …

This study aimed to see if sending text message reminders to parents could help more children get their annual flu vaccine. It involved over 228,000 children in a large pediatric care network. Researchers tested different versions of reminder texts sent to parents whose children …

This study aimed to understand how common H1N1 flu was in pregnant women and what effects it had on their pregnancies and babies during the 2009 pandemic. Researchers followed 919 pregnant women in three Paris hospitals, tracking who got infected and the outcomes. The goal was to…

This study aimed to understand how healthy adults' immune systems respond to seasonal and H1N1 (swine flu) vaccines. Researchers collected blood and nasal samples from 203 NIH employees before and after vaccination to measure immune changes. The goal was to gather detailed inform…

This study aimed to understand how a common antifungal drug, voriconazole, behaves in the bodies of critically ill patients. Researchers measured drug levels in 32 adults with severe COVID-19 or flu who were on a life support machine called ECMO and had a serious fungal infection…

This study used a nasal spray flu vaccine to create a temporary, mild 'flu-like' situation in healthy volunteers' noses. Researchers collected samples from 33 adults to measure how the body responds to influenza viruses and inflammation. The goal was to develop a safe model for s…

This study aimed to understand how often healthcare workers get the flu, both with and without symptoms. Researchers tracked 289 healthcare workers in hospitals to see how many caught the flu during the season. The goal was to measure the risk of silent transmission to patients a…

This small, early-stage study aimed to understand how the flu virus changes the community of bacteria living in the nose and throat, and how the body's immune system responds. Healthy volunteers received either a nasal spray flu vaccine or a placebo saline spray. Researchers then…

This study analyzed 10 years of anonymous French health records to understand how doctors treat common lung infections like pneumonia and bronchitis in everyday practice. It looked at over 230,000 adult patients to see what treatments were prescribed and how patients fared in the…

This study collected blood samples from children and older adults after they received their annual flu shots. Researchers wanted to analyze how people's immune systems responded to the vaccines. The blood samples were sent to major health agencies to help them make better recomme…

This study aimed to better understand why some people get very sick from H1N1 flu. Researchers analyzed fluid from the lungs of 30 patients who were so ill they needed a ventilator in the intensive care unit. By studying the virus and the body's immune response in the lungs, they…

This study followed people who survived a life-threatening lung injury from the 2009 H1N1 flu. Researchers compared two groups: those who needed a special life-support machine and those who did not. They checked lung function, quality of life, and mental health to understand the …

This study aimed to find a marker in the blood that could help doctors predict which flu patients in intensive care are most at risk of severe breathing failure or death. Researchers enrolled 227 adults and children hospitalized with confirmed flu and serious breathing problems. …

This study compared how well two different types of flu vaccines work in adults. Researchers tested traditional egg-based vaccines against newer non-egg-based vaccines to see which creates a stronger immune response. The study followed 366 adults over two flu seasons to measure t…

This study aimed to understand why the nasal spray flu vaccine provides strong, lasting protection in children but is less effective and shorter-lasting in adults. Researchers enrolled 51 healthy adults (ages 18-49) who received the FDA-approved nasal spray vaccine and provided b…