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Scientists dive deep into lungs of severe flu patients

NCT ID NCT01089400

Knowledge-focused Sponsor: Institut National de la Santé Et de la Recherche Médicale, France Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 30 people in the ICU with severe H1N1 flu who needed a breathing machine. Researchers collected fluid from the lungs to study the virus and the body's immune response. The goal was to learn more about what causes severe illness, not to test a new treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

30 people

The number who actually took part.

Start date

Oct 2009

Finished

Apr 2011

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients with severe influenza A/H1N1v infection with pulmonary involvement in intensive care unit

Ages

13 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Suspected influenza A/H1N1 infection * Diffuse bilateral pneumonia \<96h with acute lung injury or respiratory distress syndrome * Invasive or non-invasive ventilation in intensive care unit * Age \> 13 Exclusion Criteria: * Other cause identified of acute lung injury or acute respiratory distress syndrome * Contraindicated bronchoalveolar lavage

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Conditions

The condition(s) this trial relates to.

acute lung injury acute respiratory distress syndrome adult acute respiratory distress syndrome influenza Respiratory Aspiration swine influenza

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acute lung injury Acute respiratory distress syndrome Influenza

Contacts and locations

Locations

  • Pitie-Salpetrière Hospital

    Paris, France

  • Tenon Hospital

    Paris, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.