INFLUENZA

This early-stage study tests a new mRNA-based flu vaccine in 50 healthy adults aged 18 to 49. Participants receive two shots, 28 days apart, at different dose levels. The main goal is to check safety and how well the vaccine triggers an immune response, compared to a standard flu…

This study looks at how a nasal spray flu vaccine works in 60 healthy teenagers aged 14-17. Researchers will measure immune responses in the nose and blood before and after vaccination. The goal is to understand how well the vaccine protects against the flu.

This study enrolled over 15,000 military members and randomly gave them one of three flu vaccines: cell-based, recombinant, or egg-based. The goal was to see which vaccine best prevents lab-confirmed flu over four flu seasons. Results will help choose the most effective flu shot …

This study tests whether a high-dose flu vaccine works better than the standard dose for adults who have recently had a kidney, heart, or liver transplant. About 400 participants, all within 1 to 11 months after transplant, will receive either two high-dose shots, two standard-do…

This study tests whether community-based communication—like counseling, social media messages, and educational materials—can increase flu vaccination rates among people over 65 in Can Tho City, Vietnam. About 1,200 elderly participants from different neighborhoods will be randoml…

This study tests a single dose of a new flu vaccine called OVX836 in about 2,850 healthy adults aged 18 to 59. The goal is to see if it can prevent confirmed influenza A and is safe. Participants receive either the vaccine or a placebo shot, and researchers track flu cases over t…

This early-stage study tested whether a new flu vaccine with an added booster (adjuvant) is safe for people 65 and older. 80 volunteers received the vaccine and were monitored for side effects over a year. The goal was to check for any immediate or long-term reactions, not yet to…

This study compares how well two FDA-approved COVID-19 vaccines (Novavax and Pfizer-BioNTech) trigger the immune system and their side effects. About 54 healthy adults aged 18-79 with certain risk factors will receive one of the vaccines and be followed over time. The goal is to …

This early-stage trial tested the safety of a new flu vaccine with an added ingredient (adjuvant) to boost immune response. It involved 80 volunteers aged 65 and older, who were monitored for side effects over 12 months. The goal was to see if the vaccine is safe enough for furth…

This study tests a nasal spray flu vaccine in 200 people aged 3 to 17. Researchers will measure antibody levels in the nose to see how well the vaccine works. The goal is to understand the immune response and how long protection lasts.

This study tests two new e-stethoscope devices that use sound waves to detect COVID-19, flu, and RSV without needles or nasal swabs. About 300 adults at a Texas military base will have a quick, painless scan and fill out a symptom questionnaire. The goal is to see if these device…

This study tests whether taking the flu medicine oseltamivir for 5 days works as well as taking it for 10 days to prevent flu in hospital patients who were exposed to the virus. About 200 adults with flu risk factors will participate. The goal is to see if a shorter treatment is …

This study looks at whether different text message reminders can encourage more people to get their flu shot. About 100,000 patients who haven't had the flu vaccine yet will receive a text message with their clinic appointment reminder. The goal is to see which message works best…

This study tests a single-dose shot called CD388 to see if it can prevent the flu in people aged 12 and older who are at higher risk for serious flu complications. About 7,500 participants will receive either CD388 or a placebo and be monitored for up to 24 weeks. The goal is to …

This early-stage study tests a new oral drug, TRX-100, in about 105 adults with mild to moderate influenza. Participants take the study drug plus standard flu care. The main goal is to find a safe and effective dose by checking side effects and lab results. Researchers also track…

This study aims to learn more about the symptoms and health effects of COVID-19 and influenza in adults. About 1,000 people with a positive test and mild symptoms will complete online surveys over six months. No treatment is given; the goal is to understand how these illnesses af…

This study looks at how two natural compounds, Taxifolin and Ergothioneine, affect the immune system in healthy adults aged 50 to 65. Participants take these supplements for a period, and researchers measure immune cell activity. The goal is to understand if these dietary compoun…

This study looks at whether eating more fiber can change the bacteria in your gut and improve how well the flu vaccine works. About 31 adults will follow a special diet before getting their flu shot. Researchers will check if people can stick to the diet and measure their immune …

This study looks at how the bacteria in your gut and what you eat might influence how well the flu vaccine works. Researchers will collect stool samples, blood samples, and diet information from 74 adults who get their flu shot at MD Anderson. The goal is to understand the connec…

This study follows 1,500 healthy infants from birth to age 4 to learn how their first exposure to influenza—either through vaccination or natural infection—affects their immune system's response to future flu exposures. Pregnant mothers are enrolled before delivery, and their bab…

This study involves 1,000 adults who use special smell cards at home to measure their sense of smell. The goal is to see if these tests can reliably detect smell changes caused by COVID-19 and track recovery over time. Participants include people with known smell loss, those with…

This study follows 500 children under 18 who tested positive for flu, RSV, or COVID-19. Researchers measure how long the virus stays active in their bodies and how it spreads to family members and classmates. The goal is to provide better guidance on when it's safe to return to s…

This study looks at how approved seasonal flu vaccines affect the body's immune response, specifically antibodies and memory B cells, in younger adults (ages 18-50) and older adults (ages 65-80). Researchers aim to understand how age and past vaccination history change the way th…

This study looks at how getting the flu vaccine year after year changes your body's immune response. Researchers will compare two types of flu vaccines in 600 healthy adults aged 22-50 in Hong Kong. The goal is to understand why some people respond better to the vaccine and why i…