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Gut bugs may boost flu vaccine power

NCT ID NCT05239403

First seen Mar 10, 2026 · Last updated Jun 23, 2026 · Updated 19 times

Summary

This study looks at whether the bacteria in your gut and what you eat can influence how well the flu vaccine works. Researchers will collect blood and stool samples from 74 adults before and after they get their flu shot. The goal is to find links between gut microbiome diversity and a stronger immune response.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could help design personalized diets or probiotics to improve flu vaccine effectiveness.

What could go wrong

This is an observational study with only 74 participants, so results may not apply to everyone. It does not test any treatment.

Conditions

The condition(s) this trial relates to.

influenza

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.