Could 5 days of tamiflu be enough to stop the flu?
NCT ID NCT07496736
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares a 5-day versus a 10-day course of oseltamivir (Tamiflu) to prevent influenza in people exposed to the virus while in the hospital. About 200 adults with flu risk factors will be randomly assigned to one of the two treatment lengths. The goal is to see if the shorter course works just as well.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- oseltamivir
- What this could lead to
- If successful, a shorter 5-day course could be just as effective as 10 days for preventing flu after exposure, reducing side effects and costs.
- What could go wrong
- This is a non-inferiority trial, so it may show the shorter course is slightly less effective. Results may not apply to people outside hospitals or those with severe illness.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Phase 3
Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.
- Participants
-
About 200 people
The number the study aims to enrol. It can still change while the study runs.
- Started
-
Dec 2025
- Expected to finish
-
Mar 2028
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * 18 years or older * exposure to influenza during hospitalization * risk factors for influenza complications * consent for participation obtained Exclusion Criteria: * younger than 18 years * hematological malignancy * hospitalized in intensive care unit * refusal to participate
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University Medical Centre Ljubljana
Ljubljana, 1000, Slovenia
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