University Medical Centre Ljubljana

This study tests a personalized stem cell therapy for 10 people with advanced, non-ischemic heart failure who already have a mechanical heart pump (LVAD). After two months of recovery and medication optimization, each participant receives their own stem cells injected into the he…

This study tests whether a 7-day course of doxycycline works as well as the standard 14-day course for people with multiple Lyme disease rashes (multiple erythema migrans). About 200 participants will be randomly assigned to one of the two treatment lengths. Researchers will trac…

This study tests whether the steroid dexamethasone can reduce brain damage and long-term disability in adults hospitalized with tick-borne encephalitis. About 200 participants will receive either dexamethasone or a placebo alongside standard care. The main goal is to see if fewer…

This study looks at whether the drug vericiguat can improve heart function in adults with stable heart failure with reduced ejection fraction (HFrEF). About 60 participants will either take vericiguat plus their usual medications or just their usual medications. Researchers will …

This study tests whether starting two diabetes drugs early—metformin plus either oral semaglutide or empagliflozin—works better than metformin alone for controlling blood sugar in people recently diagnosed with type 2 diabetes. About 90 adults with diabetes for up to 2 years will…

This study tests whether dapagliflozin, a drug used for diabetes, can prevent heart damage caused by a common type of chemotherapy (anthracycline) in women with breast cancer. About 100 participants will take either dapagliflozin or a placebo daily during their chemo. Researchers…

This study looks at whether adding resistance training (like squats and pulling exercises with weights) to standard cycling workouts helps women with coronary artery disease improve their fitness and muscle mass more than cycling alone. About 50 women will take part in a 12-week …

This study compares different doses and lengths of amoxicillin treatment for people with erythema migrans, the classic Lyme disease rash. About 200 participants will be randomly assigned to different treatment schedules. The goal is to see which regimen best prevents later Lyme s…

This study tests three different sedatives (ketamine, nalbuphine, and dexmedetomidine) in 60 children aged 6 months to 3 years who need stitches removed after surgery for cleft lip or palate. The goal is to see which drug works fastest and safest, and which makes the procedure ea…

This study looks at whether what patients expect before treatment for early Lyme disease (the rash stage) influences how well they recover. Researchers will follow 200 people with Lyme rash, asking about their expectations and tracking symptoms for a year. They will also compare …

This study follows 120 people with tumours or diseases of the nose, sinuses, and skull base to see how they are treated and how they recover. Researchers will track survival, whether the disease comes back, and patients' quality of life. The goal is to learn more about these rare…

This study looks at how tirzepatide, a weight-loss medication, affects muscle strength, structure, and metabolism in women with obesity. Thirty premenopausal women will receive either tirzepatide or a placebo for 24 weeks. Researchers will measure body composition, muscle functio…

This study follows 250 children and adults with CTNNB1 neurodevelopmental syndrome to track their mental, physical, and social development over time. Researchers will collect data through assessments and questionnaires to better understand the condition and improve care. The stud…

This study observes how ear, nose, and throat specialists treat complicated infections of the sinuses, ears, throat, and neck in both children and adults. Researchers will track standard treatments and outcomes for 2,550 participants in Ljubljana, Slovenia. The goal is to learn c…

This study looks at whether holding a newborn skin-to-skin right after a planned C-section helps both baby and mother feel less stressed. Researchers will measure heart rate variability, a sign of how well the nervous system is adapting. About 80 full-term newborns and their moth…

This study looks at how the body regulates blood pressure and heart rate in healthy adults and older adults with high blood pressure. Participants will undergo tests like standing up and exercising on a stationary bike while their heart activity and artery stiffness are measured.…