HEALTHY SUBJECTS

This early-stage study tested a new inhaled drug called SHR-4597 in 62 people: healthy volunteers and patients with mild to severe asthma. The main goal was to see if the inhaler is safe and tolerable. Researchers gave single or multiple doses and watched for side effects. This i…

This early-stage study tested a single injection called AYP-101 in 26 healthy adults to see if it safely reduces fat under the chin. Participants were randomly assigned to receive either the active drug or a placebo. The main goal was to check for side effects and how the drug be…

This study looked at whether practicing mindfulness meditation can improve quality of life and brain activity in people with epilepsy that doesn't get better with medication. About 37 adults and teens with this type of epilepsy, plus some healthy volunteers, took part. Researcher…

This study tested whether new computer methods can make standard CT scan images sharper and more detailed. 148 adults who already needed a CT scan took part. Researchers compared the new high-resolution images to the usual ones to see if they were better.

This study looked at whether vocal exercises or breathing exercises work better to improve lung function and core stability in healthy women aged 18 to 65. Fifty women did either vocal or breathing exercises twice a week for six weeks. Researchers measured their lung capacity, br…

This early-stage study tested the safety and tolerability of multiple doses of an experimental antibiotic called zidebactam given through a vein. Twenty-one healthy adults received either the drug or a placebo. The goal was to check for side effects and how the drug moves through…

This study tested a new wearable ECG sensor (ZywieZ3) in 45 healthy adults to see if it records heart signals as well as traditional sticky electrodes. The sensor was worn for up to 10 days to check skin adhesion and signal quality. Researchers also tested if slightly moving the …

This study looked at how the drug cenerimod is broken down and removed from the body. Six healthy men aged 45 to 65 took a single dose with a radioactive marker. Researchers measured the drug in urine, stool, and breath to understand its elimination.

This study checked if a new single pill containing three cholesterol-lowering medicines (bempedoic acid, ezetimibe, and atorvastatin) works the same in the body as taking those three drugs separately. 58 healthy adults aged 18-60 each received both the combo pill and the separate…

This early-stage study tested a new drug called AZD7798 in 112 healthy volunteers and people with Crohn's disease. The main goal was to check if the drug is safe and how the body processes it. No treatment benefits were expected at this phase.

This study tested whether stretching or self-massaging the neck could improve flexibility in both the neck and the hip on the same side of the body. Thirty healthy adults each tried both techniques on separate days. Researchers measured range of motion and tissue stiffness before…

This early-stage study tested a single injection of a new drug called SHR-3167 against standard insulin glargine in 24 healthy men. The goal was to compare how the body handles blood sugar after each drug, not to treat any disease. No direct benefit to participants was expected, …

This study looked at whether a single pill containing three cholesterol-lowering medicines (bempedoic acid, ezetimibe, and rosuvastatin) works the same as taking them separately. It involved 58 healthy adults aged 18 to 60. The goal was to check if the combination pill is absorbe…

This study tested whether a single pill containing three cholesterol-lowering medicines (bempedoic acid, ezetimibe, and atorvastatin) works the same as taking them separately. It involved 58 healthy adults aged 18 to 60. The goal was to see if the combination pill is absorbed sim…

This study looked at how a drug called tolvaptan behaves in the body and whether it is safe when taken multiple times. It involved 12 healthy men aged 18 to 40. The goal was to measure drug levels and side effects, not to treat any disease.

This study looked at how the drug cenerimod affects the heart's electrical activity (QT interval) in 97 healthy adults. It also tested whether cenerimod changes how birth control pills work in the body and how charcoal influences cenerimod levels. Participants received either pla…

This study checked if two forms of an antibiotic (YHP2406 and YHR2501) are absorbed the same way in the body. It involved 63 healthy adults who took a single dose of each version. The goal was to see if they are bioequivalent, not to treat any disease.

This early-stage study tested a single dose of a new drug called SAR441255 in 48 healthy adults who were lean to overweight. The main goal was to check if the drug is safe and how the body processes it. Researchers also looked at how it affects blood sugar levels. This study does…

This study looked at how the front part of the brain helps with reasoning and categorizing things. Researchers compared healthy volunteers to people with frontotemporal dementia or progressive supranuclear palsy. They used tasks, brain scans, and mild brain stimulation to underst…

This study looked at whether platelets treated with the INTERCEPT Blood System (using LED light) and stored for 5 days still work well when given back to healthy volunteers. 40 healthy adults donated their own platelets, which were treated and stored, then compared to fresh plate…

This study tested a new radioactive tracer called [18F]-F13640 in 20 healthy adults to see how well it can image certain brain receptors (5-HT1A) using PET scans. The goal was to understand how the tracer behaves in the body and whether it gives reliable results. No treatment was…

This study used PET scans to watch brain activity while people performed thinking tasks. It included healthy volunteers and people with schizophrenia or Parkinson's disease. The goal was to learn how the frontal lobe works during thinking and how certain drugs might affect it.

This study looked at how safe two experimental antibiotics, VNRX-7145 and ceftibuten, are when given alone or together. It involved 53 healthy adults aged 18 to 55. The goal was to measure how the drugs move through the body and check for side effects, not to treat any disease.

This study looked at whether a single pill containing three cholesterol-lowering drugs (bempedoic acid, ezetimibe, and rosuvastatin) works the same as taking them separately. It involved 58 healthy adults aged 18 to 60. The goal was to measure how the drugs are absorbed and proce…

This study explored whether the time of day affects a blood test that estimates how 'old' your immune system is. Researchers measured the immune age of 50 healthy adults (ages 20-69) at three different times on the same day: morning, midday, and evening. The goal was to see if th…

This study tested the safety of a new drug called VNRX-5024 in 36 healthy adults aged 18 to 55. Participants received either the drug or a placebo, with doses increasing over time. The main goal was to check for side effects and see how the drug moves through the body. No treatme…

This study tested whether a new insulin, Insulex® R, works similarly to the standard Humulin® R in 40 healthy adults aged 18 to 55. Participants received a single injection of each insulin on separate visits, and researchers measured insulin levels and blood sugar responses. The …

This study involved 1807 healthy adults to improve the quality of MRI scans. Researchers tested different settings to make images clearer and reduce blurring. No treatment or medication was given. The goal was to make MRI technology better for future patients.

This early-stage study tested the safety and how the body processes a new drug called CKD-508. It involved 44 healthy adults who took the drug or a placebo once daily. The main goal was to check for side effects and measure drug levels in the blood, not to treat any disease.

This study looked at how brain waves change in healthy people when they are given propofol, a common anesthesia drug. Researchers used wireless devices to track brain activity from the start of anesthesia until the person lost consciousness. The goal was to better understand the …

This early-stage study tested the safety and how the body handles a new drug called MT-7117 in 40 healthy Chinese adults aged 18 to 55. Participants received either the drug or a placebo, and researchers measured drug levels in the blood and monitored for side effects. The goal w…

This study looked at whether teaching physical therapy students about the science of pain (called pain neuroscience education) changes what they know and how they feel about pain. 120 students took part. The goal was to see if this kind of education could help future therapists h…

This study tested the safety and how the body handles a new drug called LV232 in 81 healthy Chinese adults. Participants received either the drug or a placebo, and researchers monitored side effects and drug levels in the blood. The goal was to gather early safety data, not to tr…

This study looked at 70 people—some with primary myelofibrosis (a rare bone marrow disorder) and some healthy—to understand how certain immune cells called MDSCs fuel inflammation and blood vessel growth in the disease. Researchers measured these cells in blood and spleen samples…

This study checks if LV232 capsules are safe and how they move through the body in healthy Chinese adults aged 18-45. About 49 volunteers will take multiple doses or test the effect of food. The goal is to gather safety data, not to treat any disease.

This early-stage study tested the safety and tolerability of an experimental drug called TISA-818 in 49 healthy adults. Participants received either the drug or a placebo as a single or multiple daily injections. The goal was to check for side effects and how the drug moves throu…

This study tested how safe and skin-friendly different adhesives are for attaching a device that records brain activity. Thirty-four healthy adults wore the adhesives behind their ears for short and long periods. Researchers measured skin health and checked for any reactions to s…

This study looked at the genetics of a rare lung condition called combined pulmonary fibrosis and emphysema (CPFE) syndrome, which causes both scarring and air sac damage. Researchers compared 250 participants, including patients with CPFE, those with only scarring or only emphys…

This early-stage study tested the safety of a new drug called ICP-332 in 24 healthy adults. Participants received either the drug or a placebo, and researchers monitored for side effects and how the drug moves through the body. The goal was not to treat any disease but to gather …

This study looked at whether pea protein or whey protein is better for building muscle and strength in healthy young adults who started a new weight-training program. Thirty-four participants took either pea or whey protein twice daily for 8 weeks while doing resistance training …

This study tested whether a short session of neck stretching can lower blood pressure in 25 healthy adults. Researchers measured blood pressure, tissue stiffness, and heart rate before and after stretching. The goal was to see if stretching relaxes blood vessels and helps the bod…

This study tested whether two drugs, DWJ1445 and DWC202506, are absorbed into the body in the same way. It involved 70 healthy adults who received a single dose of each drug at different times. The goal was to check bioequivalence, not to treat any disease.

This early-stage study tested the safety and how the body processes a new drug called ABSK061 in 40 healthy adults aged 18 to 45. Participants took the drug as minitablets, either once or multiple times, and researchers also checked if taking it with soft foods changed drug level…

This study looked at how two anxiety medications, lorazepam and diazepam, affect memory and brain activity in healthy young adults. 22 volunteers took a single dose of one of the drugs and then performed memory tasks while their brains were scanned with fMRI. The goal was to unde…

This study looked at how much of the drug cenerimod enters the bloodstream after taking a pill. Six healthy men took one tablet and later received a tiny radioactive tracer through a vein to measure the drug's absorption. The study was done for research only and did not treat any…

This early-stage study tested the safety of a new drug called M6229 in 15 healthy adults. Participants received either the drug or a placebo as a continuous infusion over 5 days. The goal was to check for side effects and understand how the drug moves through the body, not to tre…

This early-stage study tested the safety and tolerability of a new drug called UP-818-CC in 73 healthy Chinese volunteers. Participants received either a single dose or multiple daily doses of the drug or a placebo by IV infusion. The goal was to check for side effects and how th…

This early-stage study tested the safety of a new drug, SUL-238, in 83 healthy adults aged 40 and older. Participants received either the drug or a placebo, and researchers monitored for side effects and how the drug moved through the body. The goal was simply to gather safety in…

This early-stage study tested the safety and tolerability of a new drug called TJ0113 in 130 healthy adults. Participants took the drug as a single dose, multiple doses, or after a high-fat meal to see how the body handles it. The goal was to check for side effects and measure dr…

This study tested whether doing 30 squats on an unstable surface (like a wobble board) improves balance and coordination more than squats on a stable floor. 42 healthy adults aged 18-35 participated. Researchers measured postural stability, leg coordination, and dynamic balance r…

This early-stage study looked at how a drug called N-803 affects natural killer cells collected from 10 healthy volunteers through a blood-filtering process called apheresis. The main goal was to check for side effects and see how the cells grow and multiply. The trial is complet…

This study involved 250 healthy women aged 20 to 75 to create a photographic atlas of skin aging. Researchers used a special camera (LC-OCT) to take 3D images of collagen in the skin without any needles or surgery. The goal was to understand how age and sun exposure affect collag…