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Your immune age changes with the clock: new study reveals timing matters

NCT ID NCT07169721

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study looked at whether the time of day changes a person's 'immune age' — a blood-based score that reflects how well the immune system is aging. Researchers took blood samples from 50 healthy adults aged 20 to 69 at three different times (morning, midday, and evening) on the same day. The goal was to see if the immune age score (called IMMAX) varies with circadian rhythm, which could help improve how we measure immune health.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help researchers understand how to measure immune age more accurately by accounting for time-of-day effects.
What could go wrong
This is a small observational study in healthy people, not a treatment trial. The findings may not apply to people with illnesses or different lifestyles.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

50 people

The number who actually took part.

Started

Dec 2023

Finished

Apr 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

All subjects who are willing to visit the study centre in Dortmund three times a day.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * aged \> 18 years * knowledge of German or English sufficient to provide verbal explanations and obtain written consent Exclusion Criteria: * exercise on the assessment day * acute infection * vaccination within the last 4 weeks * autoimmune disease * cancer * drugs that may influence immune cell counts * participation in other interventional studies during study period

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Leibniz Research Centre for Working and Environment and Human Factors

    Dortmund, 44139, Germany

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