Your immune age changes with the clock: new study reveals timing matters
NCT ID NCT07169721
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study looked at whether the time of day changes a person's 'immune age' — a blood-based score that reflects how well the immune system is aging. Researchers took blood samples from 50 healthy adults aged 20 to 69 at three different times (morning, midday, and evening) on the same day. The goal was to see if the immune age score (called IMMAX) varies with circadian rhythm, which could help improve how we measure immune health.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could help researchers understand how to measure immune age more accurately by accounting for time-of-day effects.
- What could go wrong
- This is a small observational study in healthy people, not a treatment trial. The findings may not apply to people with illnesses or different lifestyles.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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50 people
The number who actually took part.
- Started
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Dec 2023
- Finished
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Apr 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
All subjects who are willing to visit the study centre in Dortmund three times a day.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * aged \> 18 years * knowledge of German or English sufficient to provide verbal explanations and obtain written consent Exclusion Criteria: * exercise on the assessment day * acute infection * vaccination within the last 4 weeks * autoimmune disease * cancer * drugs that may influence immune cell counts * participation in other interventional studies during study period
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Leibniz Research Centre for Working and Environment and Human Factors
Dortmund, 44139, Germany
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