COVID19

This study checked how well the Pfizer/BioNTech COVID-19 vaccine worked in people with weakened immune systems compared to healthy people. Researchers followed 539 adults, including those with conditions like HIV, organ transplants, and cancer, measuring their antibody levels and…

This early-stage study tested a new COVID-19 vaccine called ABNCoV2 in 45 healthy adults who had never had COVID-19. The main goals were to check if the vaccine was safe and to find the best dose that creates a strong immune response with minimal side effects. Volunteers received…

This trial tested two existing anti-inflammatory drugs, ruxolitinib and fostamatinib, to see if they could prevent hospitalized COVID-19 pneumonia patients from getting sicker. The goal was to stop patients' conditions from worsening to the point of needing a ventilator or other …

This large, international study aimed to find safe and effective drug treatments for people hospitalized with COVID-19 who developed severe breathing failure. It tested several investigational drugs, including aviptadil and remdesivir, by adding them to the standard hospital care…

This study tested a new approach to find tuberculosis (TB) in young children hospitalized with severe pneumonia in six high-risk countries. Researchers wanted to see if using a fast, sensitive test on easy-to-collect samples (like nasal fluid and stool) right when a child arrives…

This small, early-stage study aimed to check if a 21-herb formula called mQFPD is safe for people with mild-to-moderate COVID-19 to take at home. Researchers compared the herbal formula to a placebo (inactive treatment) in 60 participants. The main goal was to see if the formula …

This international study tested whether inhaling a mist containing heparin, a common blood thinner, could help COVID-19 patients who need breathing machines. Researchers wanted to see if this treatment could help patients get off ventilators faster and improve survival. The trial…

This study tested whether natural supplements like omega-3 (fish oil) and black seed could boost the immune system to help people fight COVID-19. Researchers enrolled 150 hospitalized patients with confirmed COVID-19 pneumonia to see if these supplements improved recovery time an…

This small, completed study tested if adding plasma from people who recovered from COVID-19 to standard hospital treatment could help patients get better. It involved 55 hospitalized adults with COVID-19 pneumonia. Researchers compared patients who received two plasma transfusion…

This trial tested whether a combination of two existing drugs (famotidine and celecoxib) could help hospitalized COVID-19 patients recover faster and prevent severe illness in newly infected people. The study was small, with only 4 total participants, and aimed to see if this dru…

This study tested if a blood-filtering procedure called therapeutic plasma exchange (TPE) could help hospitalized COVID-19 patients with severe breathing problems. It compared standard intensive care alone to standard care plus TPE in 21 patients. The goal was to see if removing …

This study tested a gentler way to use breathing machines for hospitalized COVID-19 patients with severe lung failure. Researchers compared the standard method to an 'ultraprotective' method that uses smaller, gentler breaths. The goal was to see if this gentler approach could he…

This study tested whether the drug Aviptadil could help hospitalized COVID-19 patients with severe lung failure. 471 participants received either Aviptadil plus standard hospital care or a placebo plus standard care. Researchers tracked patients for 90 days to see if the drug imp…

This study tested whether the drug remdesivir, added to standard hospital care, could help people hospitalized with severe COVID-19 and life-threatening breathing problems. About 87 very sick patients received either remdesivir or a placebo (dummy drug) along with standard care. …

This study tested a dietary supplement called AntiCov-220, made from herbs and vitamins, to see if it could prevent and treat COVID-19. It involved 82 people who had other health conditions like HIV or hepatitis. The goal was to see if the supplement was safe and if it could help…

This study aimed to develop a new test that analyzes chemicals in a person's breath to help diagnose diseases. Researchers collected breath samples from 46 people, including healthy volunteers and patients with liver disease or COVID-19. The goal was to see if unique breath 'fing…

This study tested whether using simple box fans with special air filters and improving home ventilation could prevent Covid-19 from spreading from one infected household member to others. Researchers enrolled over 200 people living in households with at least three other people. …

This study aimed to find the best way to help patients at Utah community health centers get COVID-19 vaccines. Over 65,000 patients were involved to test two methods: sending reminder text messages, and combining texts with extra support from a 'patient navigator' to help with sc…

This study aimed to find the most effective COVID-19 testing approach to help schools reopen safely. Researchers compared two strategies across 16 middle and high schools: testing only people with symptoms versus weekly testing for everyone plus symptom testing. The goal was to s…

This study aimed to find the best way to get more people at Utah community health centers tested for COVID-19. Researchers compared sending automated text messages to sending texts plus offering help from a 'patient navigator' to overcome barriers like transportation. Over 44,000…

This early study tested if using common, store-bought mouthwashes could lower the amount of COVID-19 virus people breathe out. Researchers enrolled 34 adults who recently tested positive for COVID-19. They measured the virus in breath samples collected through a special face mask…

This study tested whether large indoor concerts could be held safely during the COVID-19 pandemic. Researchers wanted to see if requiring a negative rapid test within 3 days before the event would prevent virus transmission. They compared people who attended a concert with those …

This small, completed study tested whether a 30-week personalized walking program is safe and tolerable for cancer survivors who had been hospitalized for COVID-19. The main goal was to see if the exercise caused few or only mild side effects in this vulnerable group. Researchers…

This study tested a personalized exercise program, done partly at home and partly at a clinic, for people with chronic breathing problems like COPD or sleep apnea, and for people recovering from COVID-19. Researchers wanted to see if this 18-session program could help with common…

This study tested a new physical therapy method for patients recovering from severe COVID-19. It compared standard cycling exercise to cycling combined with functional electrical stimulation (FES), which uses small electrical pulses to help muscles contract. The goal was to see i…

This study tested whether playing motion-controlled video games in virtual reality (VR) could help people with Long COVID. Researchers compared the VR exercise program to standard exercise routines. They measured if it improved pain, fatigue, mood, and overall quality of life for…

This study tested a 6-week phone-based program called 'Heart Up!' designed to help adults with heart disease who feel hopeless. The program provided motivational support from a nurse, sometimes with extra support from a loved one, to help participants become more physically activ…

This large, completed study tested whether existing medications, repurposed for COVID-19, could help non-hospitalized adults with mild to moderate symptoms recover more quickly and reduce serious outcomes like hospitalization. Over 3,200 participants were randomly assigned to rec…

This large study tested whether seven existing medications could help people with mild to moderate COVID-19 feel better faster. Over 10,000 non-hospitalized adults with COVID symptoms received either a study drug or placebo, reporting their symptoms remotely. The goal was to find…

This study aimed to understand how many primary care health workers, like family doctors, pharmacists, and dentists, had been exposed to the COVID-19 virus by measuring antibodies in their blood. It also checked their household members. The goal was to gather data on infection ra…

This study aims to understand why some people who were hospitalized for severe COVID-19 continue to experience fatigue and exercise problems long after recovery. Researchers will measure the strength and function of breathing muscles in 50 survivors to see if muscle weakness is a…

This study aimed to understand why some people who had mild COVID-19 still experience breathlessness and fatigue long after recovery. Researchers tested 25 non-hospitalized patients to see if weakness in their main breathing muscle, the diaphragm, could be the cause. They used sp…

This study measured how well people with multiple myeloma or Waldenstrom's macroglobulinemia respond to COVID-19 vaccines. Researchers tested 146 participants' immune systems after vaccination to see if they produced protective antibodies. The goal was to understand vaccine effec…

This study followed 187 people who had COVID-19 to measure their antibody levels for two years. Researchers wanted to understand how long natural immunity lasts and whether antibodies remain effective against the virus over time. They also examined how vaccination affects antibod…

This study aimed to understand how a common antifungal drug, voriconazole, behaves in the bodies of critically ill patients. Researchers measured drug levels in 32 adults with severe COVID-19 or flu who were on a life support machine called ECMO and had a serious fungal infection…

This research project investigated how COVID-19 pandemic restrictions changed online gambling behaviors in France and Sweden. Researchers analyzed anonymous tracking data from 120,000 registered online gamblers to see if lockdowns led to more gambling or different patterns. The s…

This study aimed to understand how the immune systems of people with mild or no COVID-19 symptoms successfully fight off the SARS-CoV-2 virus. Researchers observed 57 adult outpatients who tested positive, tracking their immune responses and how quickly they cleared the virus fro…

This study looked back at how the first wave of the COVID-19 pandemic affected the care of people with multiple sclerosis (MS) when they had a relapse. Researchers compared 51 patients who had a relapse in spring 2020 to a similar group from spring 2019. The goal was to see if th…

This study aimed to understand how the COVID-19 pandemic affected the mental health of nursing home staff in France. Researchers surveyed 501 workers to measure rates of post-traumatic stress, depression, and burnout. The goal was to document the psychological impact of working t…

This study aimed to understand the long-term health effects of COVID-19 by monitoring patients after they left the hospital. Researchers gave 200 people who had COVID-19 a special wristband to wear. The device tracked their heart health, sleep, and activity while they also answer…

This study aimed to understand the psychological impact of the COVID-19 pandemic on hospital staff, especially those working in Intensive Care Units (ICUs). Researchers surveyed 701 doctors, nurses, and other caregivers to measure rates of post-traumatic stress, anxiety, depressi…

This study aimed to understand how COVID-19 affects the lungs by comparing detailed PET scans from 13 recovered patients to scans from healthy people. Researchers looked for changes in how glucose moves into lung tissue, which can indicate damage. They also scanned the same patie…

This study aimed to understand the long-term recovery process for people who survived severe COVID-19 and needed intensive care. Researchers followed 85 patients from the hospital until they returned home, tracking their physical, mental, and cognitive challenges. They compared h…

This study aimed to understand why turning critically ill patients onto their stomachs (prone positioning) helps some people with severe lung failure, including from COVID-19. Researchers used lung ultrasounds to take pictures of patients' lungs before and after they were turned …

This study followed over 1,300 adults in Luxembourg who tested positive for COVID-19. Researchers monitored their health daily for two weeks, then monthly for up to a year, using questionnaires, blood tests, and a smartphone app. The goal was to identify which factors—like sympto…

This study aimed to understand the long-term health effects of COVID-19 by tracking 6,000 adults who had symptoms and were tested for the virus. Participants completed online surveys every 3 months for 18 months to share information about their health. The research focused on ide…

This study aimed to understand how the body's immune response to COVID-19 develops and lasts over time. Researchers followed 829 adults who had a confirmed COVID-19 infection, tracking their antibody levels and checking their kidney health for a full year after diagnosis. The goa…

This study aimed to understand how people with cystic fibrosis (CF) respond to COVID-19. Researchers followed 152 children and adults with CF in Europe for two years, checking their blood for COVID-19 antibodies at regular clinic visits. The goal was to see how many got infected,…

This study aimed to understand how often and why dangerous blood clots occur in people with COVID-19. Researchers looked back at the health records of 11,000 patients who tested positive for COVID-19, tracking them for 90 days to see who developed clots, what treatments they rece…

This study aimed to understand what eye problems develop in COVID-19 patients who are critically ill in the intensive care unit (ICU). Researchers examined the eyes of 23 patients at different times during their hospital stay to look for damage to the cornea, retina, and optic ne…

This study aimed to find the best ways to encourage regular COVID-19 testing for children with intellectual and developmental disabilities (IDD) and their teachers to help keep schools safe. Researchers worked with over 1,100 participants from special schools in St. Louis and Bal…

This study aimed to understand what eye problems might develop in people who were hospitalized with severe COVID-19. Researchers examined 34 patients 4 to 6 months after they left the hospital, checking for any vision or eye health issues. The goal was to gather information, not …

This study followed 300 adults with mild to moderate COVID-19 who were not hospitalized. Researchers tracked their health for one year to understand how long symptoms last and how they affect daily life and well-being. The goal was to gather information about 'long COVID' in peop…

This study followed 332 people who were hospitalized with severe COVID-19 pneumonia requiring oxygen. Researchers checked their lung health at 3 and 6 months after leaving the hospital using scans and breathing tests. The goal was to understand how often and why some people devel…

This study aimed to understand how often severely ill COVID-19 patients on breathing machines develop dangerous fungal lung infections. Researchers observed 219 adult patients who were on ventilators for at least 3 days, using standard tests to look for infections. The goal was t…

This study looked at how strictly nursing homes in France followed COVID-19 safety rules, like visitor bans and room confinement, and whether that affected how many residents died. Researchers tracked over 12,000 residents for a year to see if strong rules lowered COVID deaths bu…

This study aimed to understand how COVID-19 spread in the Dominican Republic and what helped control it. Researchers followed over 1,000 people for a year, tracking their symptoms, checking their blood for past infections, and monitoring their handwashing habits. The goal was to …

This study followed 211 older adults who were hospitalized with COVID-19 to understand how they recover their mobility and daily function over time. Researchers tracked participants' physical abilities, breathing, and overall health after leaving the hospital. The goal was to gat…

This study aimed to better understand Long COVID by describing the wide range of symptoms and rehabilitation needs people experience up to three years after infection. It involved 355 adults from Suffolk and North Essex, UK, who had COVID-19 and were diagnosed with Post-COVID Syn…

This study followed 105 pregnant women with COVID-19 to understand how their immune response affects their babies. Researchers tracked antibody levels in mothers and newborns, and also studied how COVID-19 vaccines work during pregnancy and breastfeeding. The goal was to gather i…

This study aimed to understand how COVID-19 spread through hospitals in Bamako, Mali. Researchers tested 450 hospitalized patients and healthcare workers for current infection and past immunity. The goal was to track transmission patterns, identify asymptomatic cases, and study v…

This study aimed to understand how people with cystic fibrosis (CF) respond to COVID-19. Researchers followed 113 children and adults with CF in Europe for two years, checking their blood for COVID-19 antibodies at regular clinic visits. The goal was to see how many got infected,…

This study asked 714 breast cancer survivors about their experiences getting the COVID-19 vaccine. Researchers wanted to understand their choices, side effects, and concerns, especially about swollen lymph nodes. A key worry was whether this swelling could trigger or worsen a pai…

This study looked at how people's social and economic backgrounds affect their recovery from severe COVID-19 lung damage. Researchers followed 543 patients who needed intensive care for COVID-related breathing problems, checking their lung function and quality of life six months …

This study aimed to better understand how COVID-19 symptoms develop and change throughout the day. Researchers enrolled 214 people who tested positive for COVID-19 and had them report their symptoms twice daily via text messages for ten days. The goal was to gather detailed infor…