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Can donated plasma from COVID-19 survivors speed up recovery?

NCT ID NCT04803370

Disease control Sponsor: Hospital Son Llatzer Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether giving hospitalized COVID-19 patients two doses of plasma from people who had recovered from COVID-19, on top of standard care, helps them recover faster. 55 adults with pneumonia or low oxygen levels took part. The main goal was to see if this treatment improves their condition using a standard severity scale.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

55 people

The number who actually took part.

Started

Jul 2020

Finished

Sep 2021

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Ability to understand the HIP and sign the study IC * male or female =/\> 18 years * Patient hospitalized with a COVID-19 diagnosis by PCR on nasopharyngeal swabs or any other biological sample. * Presence of respiratory symptoms and / or fever associated with COVID-19, with clinical evolution time for COVID-19 equal to or less than 7 days. * Presence of pneumonia on chest X-ray and / or SatO2 \<94% aa. * Sequential Organ Failure Assessment (SOFA) score ≤ 6. * Accept the condition of complying with the procedures established in the protocol. Exclusion Criteria: * Patients with a previous history of allergic transfusion reaction. * Lactating or pregnant women and a positive pregnancy test. * Patients who have been treated with plasma in the 21 days prior to the screening / baseline visit. * Patients who are at the time of study, participating in another clinical trial. * Patients who haven't completed all study procedures.

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Conditions

The condition(s) this trial relates to.

COVID-19

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COVID19

Contacts and locations

Locations

  • University Hospital Son Llatzer

    Palma de Mallorca, Islas de Balears, Spain

More trials for these conditions

Other studies related to the condition(s) this trial covers.