COVID19

This study tests whether a large dose of vitamin D3 can lower the risk of death within 28 days for critically ill adults with very low vitamin D levels. About 2,400 ICU patients will receive either vitamin D or a placebo. Earlier research suggested vitamin D might reduce deaths i…

This study tests whether a single infusion of concentrated antibodies against COVID-19 can help adults with early, mild COVID-19 avoid severe illness. About 820 participants aged 55+ or with weakened immune systems will receive either the antibody treatment or a placebo. The goal…

This study tests whether immune cells (called T cells) taken from a family member who recovered from COVID-19 can safely help treat mild-to-moderate COVID-19 in hospitalized adults. The cells are designed to target the virus. The trial includes 50 participants and aims to see if …

This trial uses a flexible 'platform' design to rapidly test several potential treatments for COVID-19 in adults. It aims to find safe and effective doses that can reduce severe illness, hospitalization, and death. The study involves 600 participants and is currently recruiting.

This study tests whether hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) can improve thinking, memory, and other lingering symptoms in people with long COVID. About 91 adults who have had cognitive problems for at least 3 months after a COVID infection …

This study looks at how the COVID-19 pandemic changed outcomes for people who had surgery in Stockholm, Sweden. Researchers will track up to 300,000 patients to see if death rates, complications, or hospital stays were different during the pandemic. The goal is to understand the …

This study looks at whether people who got a flu vaccine or take certain blood pressure medicines (ACE inhibitors or ARBs) had milder COVID-19. Researchers will review hospital records of 3,000 patients admitted for any reason. The goal is to see if these treatments led to fewer …

This study aims to understand the short- and long-term health problems that can occur after a COVID-19 infection, including damage to the heart, lungs, kidneys, and other organs. Researchers will follow 650 adults in Quebec, including people who had mild or severe COVID-19, those…

This study follows 6,000 pregnant women—some vaccinated against COVID-19 and some not—to compare health outcomes for mothers and their babies. Researchers will track pregnancy complications, birth defects, and infant development up to 12 months old. The goal is to understand if C…

This study tests a program to help parents in the Bronx who are feeling stressed after the COVID-19 pandemic. About 360 parents will take part to learn ways to cope and support their children. The goal is to see if the program lowers stress and improves family well-being.

This study follows 1500 adults who had COVID-19 to see how the virus affects their heart and lungs over time. Researchers will track inflammation markers and breathing problems. The goal is to learn more about recovery and long-term effects, not to test a new treatment.

This study follows 2,000 pregnant women who received monoclonal antibodies or antiviral drugs for COVID-19 to see how these treatments affect pregnancy, newborns, and infant development up to 12 months old. Researchers compare their outcomes with those of pregnant women who did n…