COVID19
Clinical trials for COVID19 explained in plain language.
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Breathing in sleep: could a simple gas save more COVID-19 patients?
Disease control OngoingThis study compares two ways to keep critically ill COVID-19 patients sedated while on a breathing machine: standard intravenous (IV) drugs versus inhaled gases typically used in surgery. The goal is to see if the inhaled approach reduces lung swelling, improves oxygen levels, an…
Matched conditions: COVID19
Phase: PHASE3 • Sponsor: Sunnybrook Health Sciences Centre • Aim: Disease control
Last updated May 26, 2026 04:48 UTC
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Old TB vaccine shows promise in taming type 1 diabetes
Disease control OngoingThis study tests whether repeated doses of the BCG vaccine (originally for tuberculosis) can lower blood sugar levels in adults with long-standing type 1 diabetes. About 150 participants will receive either BCG or a placebo over 5 years, with researchers tracking changes in HbA1c…
Matched conditions: COVID19
Phase: PHASE2 • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated May 26, 2026 04:36 UTC
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Abandoned trial: thyroid hormone spray for COVID lungs never tested
Disease control TerminatedThis study aimed to test a thyroid hormone (T3) treatment sprayed directly into the lungs of COVID-19 patients with severe breathing failure (ARDS) who were on ventilators. The goal was to reduce lung fluid and improve recovery. However, the trial was withdrawn before any patient…
Matched conditions: COVID19
Phase: PHASE2 • Sponsor: University of Minnesota • Aim: Disease control
Last updated May 26, 2026 04:36 UTC
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COVID-19 drug trial pulled before starting
Disease control TerminatedThis study planned to test an inhaled drug called Virazole (ribavirin) in adults hospitalized with COVID-19 who had serious breathing trouble. The goal was to see if the drug could safely improve their condition. However, the study was withdrawn before any participants were enrol…
Matched conditions: COVID19
Phase: PHASE1 • Sponsor: Bausch Health Americas, Inc. • Aim: Disease control
Last updated May 26, 2026 04:36 UTC
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Baby shampoo and listerine: surprising new weapon against COVID?
Disease control OngoingThis study tests whether using a baby shampoo nasal wash and Listerine mouth gargle for 4 days can lower the amount of COVID-19 virus in the nose and throat of recently infected adults aged 18-65. Participants are randomly assigned to different wash combinations, and their virus …
Matched conditions: COVID19
Phase: PHASE2, PHASE3 • Sponsor: Milton S. Hershey Medical Center • Aim: Disease control
Last updated May 26, 2026 04:31 UTC
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Can a fruit compound tame COVID-19's deadly inflammation?
Disease control OngoingThis study tests whether fisetin, a natural substance found in fruits and vegetables, can prevent COVID-19 from getting worse in hospitalized adults. The goal is to reduce dangerous inflammation that can lead to severe illness. The trial includes 80 participants aged 60+ or young…
Matched conditions: COVID19
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated May 22, 2026 13:52 UTC
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Can tweaking online networks boost vaccine trust in at-risk communities?
Knowledge-focused OngoingThis study explores whether changing how people connect online can help improve COVID-19 vaccine attitudes and uptake among African American and other underserved groups. About 4,500 adults in the U.S. with internet access are taking part. Researchers are testing if reducing onli…
Matched conditions: COVID19
Phase: NA • Sponsor: University of Pennsylvania • Aim: Knowledge-focused
Last updated May 26, 2026 04:43 UTC
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COVID-19's toll on asthma: new study aims to uncover hidden lung damage
Knowledge-focused TerminatedThis study was designed to see if COVID-19 makes asthma worse or changes how well patients can control their asthma. Researchers planned to compare asthma patients who had a severe COVID-19 infection with those who did not, tracking their lung function and symptoms for a year. Th…
Matched conditions: COVID19
Sponsor: Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau • Aim: Knowledge-focused
Last updated May 26, 2026 04:37 UTC
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Gut bacteria may hold key to long COVID mysteries
Knowledge-focused OngoingThis study looks at how the gut microbiome (the bacteria in your digestive system) might be linked to ongoing symptoms after a severe COVID-19 infection, known as long COVID. Researchers will measure changes in gut bacteria, immune system markers, and lung function in 20 adults w…
Matched conditions: COVID19
Phase: NA • Sponsor: Medical University of Graz • Aim: Knowledge-focused
Last updated May 26, 2026 04:35 UTC
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500 COVID survivors tracked to uncover lingering health mysteries
Knowledge-focused OngoingThis study follows 500 adults who had COVID-19 to learn about long-term health issues like tiredness, shortness of breath, and lung scarring. Researchers will track recovery patterns and identify who is most at risk for lasting problems. No new treatments are tested; the goal is …
Matched conditions: COVID19
Sponsor: Vanderbilt University Medical Center • Aim: Knowledge-focused
Last updated May 22, 2026 13:54 UTC
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Researchers track quarantine habits to Fine-Tune COVID-19 rules
Knowledge-focused OngoingThis study follows 1,000 people in Australia to see how well they follow COVID-19 rules like quarantine and social distancing. Researchers will also look at the health, social, and money problems these rules cause. No treatments or vaccines are tested—the goal is to learn how to …
Matched conditions: COVID19
Sponsor: Macfarlane Burnet Institute for Medical Research and Public Health Ltd • Aim: Knowledge-focused
Last updated May 22, 2026 13:53 UTC
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New MRI study aims to uncover hidden lung damage in COVID and chronic disease
Knowledge-focused TerminatedThis study uses special MRI scans with inhaled gases to see how lungs work in people with asthma, COPD, or COVID-19 (including Long COVID). Researchers will track up to 160 participants over several years to understand how these diseases change the lungs over time. The goal is to…
Matched conditions: COVID19
Sponsor: Sheffield Teaching Hospitals NHS Foundation Trust • Aim: Knowledge-focused
Last updated May 20, 2026 11:53 UTC
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Hospital staff antibody study reveals vaccine response over a year
Knowledge-focused OngoingThis study looks at how well the AstraZeneca COVID-19 vaccine works in 200 hospital employees. Researchers measure antibody levels in the blood at 6 weeks, 6 months, and 12 months after vaccination. The goal is to understand how long the immune protection lasts and how many peopl…
Matched conditions: COVID19
Phase: NA • Sponsor: Universitair Ziekenhuis Brussel • Aim: Knowledge-focused
Last updated May 19, 2026 12:01 UTC
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COVID-19's hidden toll on organs: diabetes connection explored
Knowledge-focused OngoingThis study looks at how COVID-19 may change organs like the heart, lungs, or kidneys in people who have diabetes and those who don't. Researchers will use scans to measure organ size and other changes in 35 adults who had COVID-19. The goal is to learn more about long-term effect…
Matched conditions: COVID19
Sponsor: AdventHealth Translational Research Institute • Aim: Knowledge-focused
Last updated May 13, 2026 15:58 UTC
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University survey reveals mixed feelings on online classes during pandemic
Knowledge-focused TerminatedThis study surveyed over 9,000 undergraduate students and teaching staff at Misr International University in Egypt to understand their satisfaction with online learning during the COVID-19 pandemic. The goal was to compare perceptions and gather feedback on the shift to virtual c…
Matched conditions: COVID19
Sponsor: Misr International University • Aim: Knowledge-focused
Last updated Apr 24, 2026 16:20 UTC
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Miniature camera peers into lungs to unlock CF mysteries
Knowledge-focused OngoingThis study tests a new, tiny camera (micro OCT) that can take detailed pictures of the airways in the lungs and nose. Researchers want to see if it works well in adults with cystic fibrosis and healthy volunteers. The goal is to better understand early lung damage, which could le…
Matched conditions: COVID19
Sponsor: University of Alabama at Birmingham • Aim: Knowledge-focused
Last updated Apr 24, 2026 16:07 UTC