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Could a natural compound calm COVID-19's deadly inflammation?

NCT ID NCT04476953

First seen Nov 01, 2025 · Last updated Apr 29, 2026 · Updated 26 times

Summary

This study tests whether fisetin, a natural senolytic drug, can prevent COVID-19 from getting worse by calming the body's excessive inflammatory response. About 80 hospitalized adults aged 60+ (or 18-59 with certain health conditions) will receive fisetin or a placebo. The goal is to see if fisetin improves oxygen levels and reduces serious complications.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Mayo Clinic in Rochester

    Rochester, Minnesota, 55905, United States

Conditions

Explore the condition pages connected to this study.