COVID19

This study is testing whether giving high doses of vitamin D3 to critically ill patients with very low vitamin D levels can reduce the chance of death within 28 days. The trial will include 2,400 adults in intensive care units. If successful, this cheap and easy treatment could b…

This study tests several potential COVID-19 treatments in adults to find safe doses and see if they help patients recover faster. It uses a flexible 'platform' design to add new drugs quickly. The trial includes people with mild to severe COVID-19 and focuses on reducing symptoms…

This study is testing whether a drug called defibrotide is safe and feasible for people with severe COVID-19 pneumonia. About 42 adults with confirmed COVID-19 and lung infiltrates will receive the drug. The main focus is on monitoring for serious side effects like bleeding and l…

This study tests whether special immune cells (called T cells) taken from a family member who already recovered from COVID-19 can safely treat mild to moderate COVID-19 in hospitalized adults. The cells are designed to attack the virus. The trial involves 50 participants and aims…

This study aims to help parents in the Bronx who are feeling stressed after the COVID-19 pandemic. It offers a program to reduce stress and improve how parents support their children. About 390 caregivers will take part. The goal is to see if the program lowers stress and helps f…

This study tests whether hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) can improve thinking, memory, and other symptoms in people with long COVID. About 91 adults who have had cognitive problems for at least 3 months after a COVID infection will recei…

This registry is enrolling 2000 pregnant women who received COVID-19 treatments like antiviral drugs or monoclonal antibodies. Researchers will track pregnancy outcomes, baby health, and development up to 12 months after birth. The goal is to better understand the safety of these…

This study collects blood and nasal secretions from up to 2,000 people with COVID-19 to learn why some get very sick while others recover easily. Researchers will also track long-term symptoms like fatigue and brain fog. No treatments are tested—the goal is to gather data to guid…

This study aims to understand why some people lose their sense of smell after a COVID-19 infection and why it doesn't come back. Researchers will collect tiny tissue samples from the nose of 240 people—some with smell problems and some without—to look for differences in cells, in…

This study follows 6,000 pregnant women worldwide to compare health outcomes for those who received a COVID-19 vaccine during pregnancy versus those who did not. Researchers will track pregnancy complications, newborn health, and infant development up to 12 months old. The goal i…

This study uses a special PET-CT scan to track immune cells in people who have recovered from COVID-19. Up to 80 adults who had COVID-19 will get a tiny dose of a tracer to see where immune cells are active in their bodies. The goal is to learn more about how the immune system re…

This study looks back at 3,000 hospital patients to see if those who got a flu shot, took blood pressure meds (ACEI/ARB), antihistamines, or amantadine had better COVID-19 outcomes. Researchers want to know if these common treatments can reduce deaths or shorten hospital stays. N…

This study looks at 300,000 surgical patients in Stockholm to see how the COVID-19 pandemic impacted their recovery. Researchers will track deaths, complications, and how long people stayed in the hospital. The goal is to understand the pandemic's effects on surgical care, not to…

This study follows 1500 adults who had COVID-19 to see how the virus affects their heart and lungs over time. Researchers will track inflammation markers and breathing problems using questionnaires. The goal is to learn more about recovery, not to test a treatment.

This study follows 650 adults in Quebec to learn about the short- and long-term health problems caused by COVID-19, including damage to the heart, lungs, kidneys, and other organs. Participants include people who had mild, moderate, or severe COVID-19, as well as those who never …