COVID19

This study tests whether a single infusion of hyperimmune immunoglobulin (hIVIG) — concentrated antibodies from recovered COVID-19 patients — can help adults at high risk (age 55+ or with weakened immune systems) who have early COVID-19. Participants receive either the antibody i…

This study tests whether giving inhaled anesthetics (isoflurane or sevoflurane) to sedate COVID-19 patients on ventilators can improve survival and reduce time on the breathing machine compared to standard IV sedatives. About 800 adults in ICUs who need a ventilator will be rando…

This study tests whether fisetin, a natural substance found in fruits and vegetables, can reduce severe inflammation in adults hospitalized with COVID-19. The trial includes 80 participants aged 60+ or younger adults with certain health risks. Researchers will monitor side effect…

This study planned to test an inhaled antiviral drug called Virazole (ribavirin) in hospitalized adults with COVID-19 who had serious breathing trouble. It was a very early Phase 1 trial focused on safety and how well patients improved. However, the study was withdrawn before any…

This study tests whether repeated doses of the BCG vaccine (originally for tuberculosis) can help adults with long-standing type 1 diabetes lower their blood sugar levels. About 150 participants receive either BCG or a placebo over 5 years, with follow-up for 10 years. The goal i…

This study planned to test a thyroid hormone (T3) given directly into the lungs of COVID-19 patients with severe breathing failure (ARDS) who were on ventilators. The goal was to reduce lung fluid and improve recovery. However, the trial was withdrawn before any patients were enr…

This early-stage trial tests a biologic treatment for 20 people with moderate COVID-19 who also have controlled cancer. The treatment aims to help the immune system recognize and kill the virus. Researchers will check if the virus clears and if the immune response improves.

This study tested whether using a baby shampoo nasal wash and Listerine mouthwash for 4 days could lower the amount of COVID-19 virus in the nose and throat of recently infected adults aged 18-65. Participants were randomly assigned to different wash combinations, including plain…

This study follows 500 adults who had COVID-19 to see what health problems they face months later. Researchers will track symptoms like tiredness, breathing trouble, and lung damage. The goal is to learn how common these long-term issues are and who is most likely to have them.

This study is testing a tiny camera called micro OCT that can take detailed pictures of cells inside the lungs and nose. Researchers want to see if it works well in people with cystic fibrosis and other lung conditions. The goal is to eventually use this imaging to detect early d…

This study was designed to track how COVID-19 infection might worsen the condition of people with inherited metabolic diseases (IMD). Researchers planned to collect information from French patients with IMD who had or had COVID-19 to see how often their metabolic disease got wors…

This study follows 1,000 Australians to see how well they follow COVID-19 rules like quarantine and distancing. Researchers also track the social, economic, and mental health effects of these measures. No treatment or vaccine is tested—the goal is to learn how to make public heal…

This study uses advanced MRI scans with special gases to see how lungs work in people with asthma, COPD, or COVID-19 (including Long COVID). Researchers will track up to 160 patients over several years to understand how these diseases change the lungs over time. The goal is to le…

This study looks at organ changes in people recovering from COVID-19, comparing those with and without type 2 diabetes. Researchers will use scans to measure organ size and volume. The goal is to learn more about how COVID-19 affects the body long-term in diabetic patients.

This study looks at how long COVID-19 neutralizing antibodies stay in the blood of elderly nursing home residents. Researchers will take blood samples from 98 participants to measure antibody levels over time. The goal is to understand how aging affects the immune response to COV…

This study aimed to see if COVID-19 makes asthma worse or harder to control. Researchers planned to compare asthma patients who had COVID-19 with those who did not, tracking lung function and symptoms for a year. However, the study was withdrawn before enrolling anyone, so no res…

This study explores whether specially designed online social networks can improve COVID-19 vaccine attitudes and intentions among at-risk populations, including African American and Latinx communities. Over 4,400 participants in the US will be placed in different online groups an…

This small pilot study looks at how the gut microbiome might be linked to lingering symptoms after severe COVID-19. Researchers will measure changes in gut bacteria, immune markers, and lung function in 20 adults who had severe COVID in the past year. The goal is to find better w…

This study aimed to understand how undergraduate students and teaching staff at Misr International University in Egypt felt about online learning during the COVID-19 pandemic. Over 9,000 participants were asked about their satisfaction and knowledge through questionnaires. The go…

This study follows 200 hospital employees who received the AstraZeneca COVID-19 vaccine. Researchers measure their antibody levels at 6 weeks, 6 months, and 12 months after the second dose to see how long protection lasts. The goal is to understand the immune response and help gu…

This study aimed to collect medical information from people who developed unusual blood clots within four weeks of receiving a COVID-19 vaccine. The goal was to better understand any possible link between the vaccine and these rare events. However, the study was withdrawn before …