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Baby shampoo and mouthwash may fight COVID-19, study finds

NCT ID NCT04802408

Disease control Sponsor: Milton S. Hershey Medical Center Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early This study
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Sep 15, 2026 · Updated 2 times

Summary

This study tested whether using a baby shampoo nasal wash and Listerine mouthwash for 4 days could lower the amount of COVID-19 virus in the nose and throat of recently infected adults aged 18-65. Participants were randomly assigned to different wash combinations, including plain salt water as a comparison. The goal was to see if these simple, at-home rinses could safely reduce viral load.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 2/3

Runs two stages together: whether the treatment works, then large-scale confirmation.

Participants

171 people

The number who actually took part.

Started

Oct 2021

Finished

May 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. A first-time positive test for SARS-CoV-2 infection within 5 days of enrollment 2. Adults who are ≥18 -65 years of age 3. Currently in isolation 4. Symptomatic or asymptomatic from SARS-CoV-2 Exclusion Criteria: 1. History of nasal or sinus surgery 2. Non-English speaking 3. Lack of electronic device (computer, mobile phone etc.) on which to access an app for study data collection. 4. Adults that need inpatient care for COVID-19 or any of its complications. 5. Adults that give a history of being unable to tolerate gargles or nasal washes. 6. Adults who do not give informed consent for study participation. 7. History of a Covid vaccine booster 8. A history of use of nasal or oral washes after SARS-CoV-2 test sample collection. 9. Prisoners 10. Adults that give history of current pregnancy (NO KNOWN CONTRAINDICATION TO PREGNANCY) 11. History of monoclonal antibody treatment 12. History of or current molnupiravir treatment

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Conditions

The condition(s) this trial relates to.

COVID-19 severe acute respiratory syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COVID19 SARS-CoV infection

Contacts and locations

Locations

  • Penn State

    State College, Pennsylvania, 16801, United States

  • Penn State Health Milton S. Hershey Medical Center

    Hershey, Pennsylvania, 17033, United States

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