Blow into this tube: a new breath test could spot liver cancer and COVID-19
NCT ID NCT04341012
First seen Jan 31, 2026 · Last updated Jun 23, 2026 · Updated 17 times
Summary
This study by Mayo Clinic tested whether analyzing chemicals in a person's breath could help diagnose or predict the course of liver disease, liver cancer, and COVID-19. Researchers collected breath samples from 46 participants and looked for unique patterns of volatile organic compounds. The goal was to develop a simple, non-invasive clinical test, but the study was small and focused on building the method, not yet proving it works for routine diagnosis.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Mayo Clinic Florida
Jacksonville, Florida, 32224, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
breath sample analysis
What this could lead to
If successful, this could lead to a simple, non-invasive breath test to help diagnose or predict the course of diseases like liver cancer and COVID-19.
What could go wrong
This is a small, early-stage study (46 participants) focused on developing the test, not proving it works for diagnosis. The results may not apply to larger or different populations.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.