CEREBRAL PALSY

This study looks at whether giving iron supplements to children with low iron before hip surgery can reduce the need for blood transfusions and improve recovery. The trial involves 180 children aged 0-18 who are scheduled for specific hip surgeries, many of whom have cerebral pal…

This study tests whether starting a personalized home therapy program soon after birth can reduce the severity of cerebral palsy in babies at high risk. Researchers will compare motor skills at age 2 between infants who receive the early program and those who get standard care. T…

This program gives children under 26 with brain conditions like cerebral palsy or stroke access to umbilical cord blood infusions. The cord blood is given through an IV and may help the brain repair itself. It is not a cure, but aims to improve symptoms and quality of life.

This study tests a special hand exercise program for children aged 6-12 with spastic cerebral palsy. The goal is to see if it improves their grip strength and ability to move objects in their hand. Fourteen children will do the exercises for 10 weeks, and their progress will be m…

This study tests whether giving magnesium sulphate to pregnant women at high risk of early delivery can lower the chance of their baby developing cerebral palsy. About 138 women between 32 and 35 weeks of pregnancy will receive either the drug or a placebo before birth. Researche…

This study tests whether adding cognitive sensory motor training to regular physical therapy can improve hand and arm function in children with cerebral palsy. Thirty-two children aged 6 to 12 will be split into two groups: one gets the extra training plus routine therapy, the ot…

This study tests whether a child-focused goal-setting method called ENGAGE helps kids with disabilities like autism or cerebral palsy get more out of therapy. About 96 children aged 5-12 and their therapists will be split into two groups: one using ENGAGE and one using usual care…

This study explores whether aquatic therapy in a warm pool can help children ages 3-9 with cerebral palsy or similar movement problems. Over ten weeks, kids attend pool sessions twice a week to improve swim safety, arm function, and daily self-care. Researchers will measure chang…

This study compares two ways of making ankle-foot braces (AFOs) for people with leg weakness from conditions like cerebral palsy, stroke, or spinal cord injury. The traditional method uses a plaster cast, while the newer method uses 3D scanning and printing. Researchers want to s…

This study looks at whether a 10-week adapted dance program can improve balance, walking ability, and quality of life for children with cerebral palsy. Twenty participants aged 4 to 17 will take dance classes and be tested before and after the program. The goal is to see if danci…

This study tests whether a safe, non-invasive device that stimulates the vagus nerve can help teens with cerebral palsy improve arm and hand movement when used during physical therapy. Ten adolescents aged 12-17 with spastic cerebral palsy will receive the treatment to see if it …

This study tests whether a special compression garment called the SPIO Core-Max can help infants with cerebral palsy control their head, trunk, and arms better. About 30 babies aged 6 to 18 months will wear the brace and be tracked for 6 months. The goal is to see if it improves …

This study tests whether behavioral coaching, combined with wearable activity monitors, can help people with cerebral palsy take more steps each day. Researchers will track changes in walking speed, balance, and brain activity. The goal is to find a simple, non-drug strategy to i…

This study explores whether using a ride-on toy can motivate children with cerebral palsy to use their weaker arm and hand more. Ten children will participate in a 6-week program where they drive the toy while wearing a mitten on their stronger hand. Researchers will measure chan…

This study tests a special therapy called HABIT-ILE that combines intensive hand, arm, and leg exercises for children with spastic cerebral palsy. The goal is to see if it improves both motor skills and thinking abilities like memory and attention. 42 children will receive 90 hou…

This study aims to see if a special neck brace can help children with cerebral palsy improve their head and neck movement. Researchers will work with 30 children who have significant movement challenges. The study involves 12 training sessions with the brace, plus follow-up visit…

This study tests a new therapy to help children with cerebral palsy walk better. The therapy involves 30 hours of practice over 6 weeks, done at home. Researchers want to see if children and families find it helpful and easy to stick with. The study includes 14 children and uses …

This study tests whether a therapy done at home via video calls can help infants with cerebral palsy use their weaker arm more. About 267 babies aged 4 to 13 months will be assigned to different sequences of the therapy or standard care. The goal is to see if the therapy improves…

This study looks at whether a mild, non-invasive stimulation on the back (like a light tap) can reduce muscle tightness (spasticity) in children with cerebral palsy. About 30 children aged 5 to 17 will do movement exercises and receive the stimulation to see if it helps their mus…

This study looks at whether adding a single session of whole-body vibration to treadmill training can improve walking and reduce leg stiffness in children with cerebral palsy. About 20 children aged 6–17 who can walk will participate. The goal is to see if the combination works b…

This study is testing two new ways to help children with cerebral palsy walk better. One method uses targeted resistance training for the ankle muscles, and the other uses a device that gives adaptive ankle assistance during walking. The goal is to see if these approaches improve…

This study looks at whether adding whole-body vibration (gentle shaking while standing) to the usual serial casting process can improve ankle movement faster in children with cerebral palsy. About 45 kids aged 3 to 17 who need ankle casting will take part. The goal is to see if t…

This study tests a new home-based program that uses a virtual reality treadmill to help children aged 6 to 17 with conditions like cerebral palsy, neuromuscular diseases, or obesity improve their walking. The program involves at least three 30-minute sessions per week combining w…

This study is testing whether a mobile health app can help people with chronic conditions like spinal cord injury, cerebral palsy, spina bifida, or traumatic brain injury better manage their health and improve their quality of life. About 160 participants aged 12 and older who li…

This study tests a motor training program called 'Let's Move' for infants aged 3-8 months who are at high risk for cerebral palsy. The goal is to see if the program is practical and acceptable for families, and whether it helps improve motor skills. About 35 infants will take par…

This study tests a program called Therapy Together for young children (ages 3 months to 5 years) with cerebral palsy who have limited use of one hand. The program uses gentle exercises and activities over 8 weeks to improve hand function and daily skills. Researchers want to see …

This study tests whether specially designed video games (serious games) can improve balance, memory, and quality of life in 30 children with cerebral palsy. The games combine movement and thinking tasks, offering a fun way to enhance traditional therapy. Researchers will measure …

This study tests whether adding playful nerve-mobilization activities to standard physical therapy can improve hand grip strength and dexterity in children with cerebral palsy. About 34 children aged 6 to 12 with diplegic CP will be randomly assigned to either routine therapy alo…

This study tests a robotic leg brace (exoskeleton) designed to improve walking in children aged 3 to 17 with conditions like cerebral palsy, spina bifida, muscular dystrophy, or incomplete spinal cord injury. The device can assist or resist leg movement during walking. The trial …

This study aims to improve early diagnosis of cerebral palsy (CP) by scanning babies' brains during natural sleep using advanced MRI. Researchers will follow about 200 infants—some at risk for CP and some typically developing—from 3 months to 2 years old. They will compare brain …

This study follows 100 infants diagnosed with or at high risk for cerebral palsy from birth to age 2. Researchers will regularly measure motor skills, speech, thinking, movement, and other abilities to map how the condition naturally unfolds. The goal is to better understand earl…

This study is testing whether a smartphone app can accurately measure how children with cerebral palsy move, like jumping and walking. Researchers want to see if the app works as well as expensive lab equipment, so kids can be assessed at home or school. About 60 children aged 6 …

This study aims to diagnose cerebral palsy (CP) earlier in babies who are at high risk, such as those born prematurely or with brain injuries. Researchers will use brain scans, sleep tests, and blood markers to predict which infants will develop CP and other developmental issues.…

This study is testing whether the EXOPULSE Mollii Suit can improve balance and reduce fall risk in people with cerebral palsy, multiple sclerosis, stroke, or fibromyalgia. Researchers will track changes in balance scores and walking speed over time. The goal is to identify which …

This study is building a national database of people with cerebral palsy (CP) in Switzerland. Researchers will collect information on diagnosis, treatments, and daily life from up to 15,000 participants. The goal is to monitor health trends, support research, and improve care and…

This study aims to create better methods for measuring arm and hand movements in infants, including those with perinatal stroke or cerebral palsy. Researchers will analyze video recordings and developmental tests from 80 children (8-36 months old) to build a new assessment tool c…

This study tests a new, non-invasive sensor to detect lung problems in 250 children with severe cerebral palsy. The goal is to create a simple screening tool for respiratory distress and to see how lung function relates to scoliosis. Participants wear a sensor that measures breat…

This study is creating a shared database of information from up to 100 children who have had or will have deep brain stimulation (DBS) for conditions like dystonia, epilepsy, or Tourette syndrome. By combining data from multiple hospitals, researchers hope to learn which children…

This study looks at a small leg muscle called the plantaris and its role in treating tight ankles (ankle equinus) in children aged 4-17. About 42 kids having surgery for this condition will have the plantaris and larger calf muscles lengthened in a random order. The goal is to se…

This study looks at how movement and thinking skills are connected in people with brain damage from conditions like cerebral palsy or stroke. Researchers will use a robotic tool to measure arm movements and thinking tasks in 400 participants aged 3 to 90. The goal is to better un…

This study looks at sleep quality in children with cerebral palsy (ages 2–18) and how it affects the well-being of their parents or guardians. Researchers will use questionnaires to measure sleep problems in both children and caregivers, along with caregiver burden and mental hea…

This study follows 1,000 infants with brain injuries to create a computer model that can predict if a baby will develop cerebral palsy and how severe it might be. Parents fill out two online questionnaires about their experiences over the first two years. No extra tests are neede…

This study aims to understand how brain and spinal cord activity differs in people with cerebral palsy compared to those without. Researchers will use brain scans and mild electrical stimulation to measure these differences. The goal is to learn more about the condition, not to p…

This study tests whether brain-computer interfaces (BCI) can be used at home by children aged 5-18 with severe physical disabilities, such as cerebral palsy or brain injury. The goal is to see if BCI helps them achieve personal life participation goals and if the program can reac…

This study looks at how children and young adults with cerebral palsy (CP) move, using special sensors like ultrasound, EEG (brain wave cap), and muscle stickers. Participants will do simple movements with and without a robotic leg brace. The goal is to gather data to make future…

This study looks at data from children with movement problems caused by conditions like cerebral palsy, autism, or brain injury. The children receive intensive, play-based therapy for several hours a day over weeks. The goal is to understand how well this therapy helps them gain …

This study looks at a special clinic called the Transitional and Lifelong Care (TLC) program, designed for adults with conditions like cerebral palsy, spina bifida, or developmental disabilities that started in childhood. The goal is to see if this clinic helps patients and their…

This study looks at how hand sensation (like touch and vibration) affects daily activities in children with cerebral palsy aged 6 to 15. Researchers will compare 12 children with cerebral palsy to 12 typically developing children using simple tests and parent questionnaires. The …

This study tests small, wearable motion sensors (IMUs) to measure walking in healthy children and children with cerebral palsy. The goal is to see if these sensors can accurately track walking speed and movement in real-life settings, unlike current lab-based systems. 80 children…

This study uses safe brain imaging techniques (NIRS and EEG) to see how the brain controls movement in people with cerebral palsy and healthy volunteers. Researchers will compare brain activity patterns and test if biofeedback training can help improve movement coordination. The …

This study aims to find out if adults with cerebral palsy experience changes in their brain and spinal cord structure over time. Researchers will analyze past and new MRI scans from 30 participants aged 18-80 to see if brain shrinkage relates to loss of function. The goal is to b…

This study tests whether a virtual version of the Abecedarian Approach, an early learning program, works as well as in-person sessions for children aged 0-5 who had a brain injury at birth (HIE) or were born very prematurely. Researchers will enroll 225 families in rural areas to…

This study follows 500 children with cerebral palsy who are having leg or spine surgery. Researchers want to understand how pain changes over time and what factors lead to long-term pain. Participants will fill out surveys and do sensory and movement tests before and after surger…