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New study uses MRI to track brain aging in cerebral palsy

NCT ID NCT07433647

Knowledge-focused Sponsor: Columbia University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is looking at whether the brains and spinal cords of adults with cerebral palsy shrink or change over time, which might explain why some people lose function as they age. Researchers will collect and compare past and new MRI scans from 30 adults with CP across the U.S. The goal is to better understand if these changes are like neurodegeneration, not to test any treatment.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help explain why some people with cerebral palsy experience a decline in function as they age, pointing toward future therapies.
What could go wrong
This is an observational study with only 30 participants, so findings may not apply to everyone with cerebral palsy. It looks at past scans and does not test any treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 30 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2023

Expected to finish

Jul 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

People with cerebral palsy across the United States

Ages

18 to 80 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Have multiple MRI scans of brain and/or spinal cord spaced at least 24 months apart * Between 18-80 years of age with at least one MRI scan after the age of 18 * No known central or peripheral neurological disease or injury other than cerebral palsy causing brain degeneration * Inclusion in CPRN registry * diagnosis of Cerebral Palsy * \>18 years of age * Have received at least one past brain MRI scan as part of standard care (patients who have two or more brain MRI scans can be included in the retrospective arm only) Exclusion Criteria: * History of more than one seizure in lifetime * History of known degenerative genetic disorder * History of brain tumor, abscess, or multiple sclerosis * History of moderate or severe head trauma * History of metal implants in head

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Conditions

The condition(s) this trial relates to.

cerebral palsy hemiplegia quadriplegia spastic diplegia spastic hemiplegia spastic quadriplegic cerebral palsy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cerebral palsy Spastic diplegia Spastic hemiplegia Spastic quadriplegia

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Weinberg Family Cerebral Palsy Center, Columbia University

    RECRUITING

    New York, New York, 10040, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.