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Zapping the spine: a Non-Invasive device aims to loosen stiff muscles and improve walking in cerebral palsy

NCT ID NCT07826494

Symptom relief Sponsor: University of Washington Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 17, 2026 · Last updated Sep 18, 2026 · Updated 1 time

Summary

Researchers at the University of Washington are testing whether non-invasive spinal stimulation can temporarily reduce muscle stiffness and improve walking in people with cerebral palsy. The study includes 20 participants aged 4 to 65 who can walk for at least 10 minutes. Participants walk on a treadmill both with and without the stimulation, and researchers measure changes in muscle stiffness, step length, and overall gait quality.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
non-invasive transcutaneous spinal stimulation using a device called SpineX or xStep
What this could lead to
If it works, this could offer a drug-free way to ease muscle stiffness and improve walking for people with cerebral palsy.
What could go wrong
This is a small, early study of 20 people looking only at short-term effects during a single walking session. Any improvements may not last, and the approach may not help everyone with cerebral palsy.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 20 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2026

Expected to finish

Dec 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

4 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Individuals who: * have a diagnosis of spastic cerebral palsy or high likelihood of CP diagnosis * are 4-65 years of age * have spasticity in lower-extremity muscles * are at a functional Gross Motor Function Classification System (GMFCS) Level I-III * can walk for at least 10 minutes with/without support * can understand and follow simple directions * have a stable medical condition, as reported by the caregiver/parent Exclusion Criteria: Individuals who: * who have had lower-extremity surgery or injury in the prior 12 months * have had botulinum toxin injections in the prior 3 months * have had selective dorsal rhizotomy (SDR) in the past * have uncontrolled seizures * have significant cardiovascular or musculoskeletal disease that would prevent full participation * are dependent on ventilation support * have implanted stimulator (e.g. epidural stimulator, vagus nerve stimulator, pacemaker, cochlear implant, etc) or drug delivery device (e.g. baclofen pump) * have established osteoporosis and taking medication for osteoporosis treatment. * have rheumatic diseases (rheumatoid arthritis, systemic lupus erythematosus, etc.) * have active cancer * have received stem cell injections into the spinal cord

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Conditions

The condition(s) this trial relates to.

cerebral palsy spastic cerebral palsy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cerebral palsy

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

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Contacts and locations

Locations

  • University of Washington

    RECRUITING

    Seattle, Washington, 98195, United States

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