CATARACT

This study tests whether a tiny implant that releases medication inside the eye can control eye pressure as well as standard eye drops in people with glaucoma or high eye pressure who are also having cataract surgery. About 400 adults will receive either the implant plus a specia…

This early-stage study tests the safety of an experimental eye injection called EO2002 given right after cataract surgery. The goal is to see if it can help protect the thin layer of cells on the inside of the cornea, which often gets damaged during surgery. About 32 adults with …

This study looks at whether placing a small support ring (capsular tension ring) during cataract surgery helps keep the artificial lens more stable in people who also have retinitis pigmentosa, an eye disease that causes vision loss. Each of the 88 participants will get the ring …

This study tests whether eye drops made with stem cells can help people with dry eye disease and cataracts. The drops aim to reduce inflammation and repair the eye's surface. About 300 adults aged 18 to 80 with dry eye will receive the treatment. The study will measure tear film …

This study tests a special cleaning tool called the Tran cannula during cataract surgery in people with pseudoexfoliative glaucoma. The goal is to see if it lowers eye pressure better than extra eye rinsing. About 58 adults with both conditions will take part.

This study tests whether a tiny implant that releases eye-pressure-lowering medicine, placed during cataract surgery, works better than standard eye drops. About 400 adults with mild-to-moderate glaucoma or high eye pressure who need cataract surgery will take part. The goal is t…

This study tests whether a nose spray medication (dexmedetomidine) can help control blood pressure in elderly patients with high blood pressure who are having cataract surgery. About 126 people aged 65 and older will be randomly assigned to receive either the drug or a placebo be…

This study is checking the long-term safety of the IC-8 Apthera lens, which is used during cataract surgery to help with both distance and near vision. After surgery, some people develop a cloudy film behind the lens (called PCO), which is treated with a laser. The study will fol…

This study compares two different trifocal toric lens implants used during cataract surgery to correct cataracts, astigmatism, and presbyopia (difficulty seeing up close). About 138 adults with regular corneal astigmatism will receive one of the two lenses. The main goal is to se…

This study is testing whether a simple vision screening done in a regular doctor's office can help find vision problems early in people over 70 who have at least one chronic condition like diabetes or high blood pressure. About 460 participants will be invited to take vision test…

This study is testing a new robotic system called ORYOM to help surgeons perform cataract surgery. The goal is to see if the robot can safely complete the surgery without needing to switch to a manual method. About 20 people aged 55 to 80 who need cataract surgery will take part.…

This study compares two types of artificial lens implants (Clareon Vivity and PureSee) used in cataract surgery. Researchers want to see which lens provides better vision at different distances. About 80 adults aged 50 and older with age-related cataracts will take part. Each per…

This study compares three sedation methods (dexmedetomidine, propofol, or both) in 1,000 adults having cataract surgery. The goal is to see which approach provides the best comfort and safety, including effects on heart rate, breathing, and side effects like nausea. Participants …

This study looks at how well a new lens implant (Clareon PanOptix Pro) works for people who have cataracts and previously had LASIK or PRK to correct nearsightedness. About 40 adults aged 45 and older will receive the lens in both eyes and be followed for 3 months. The goal is to…

This study compares two types of advanced intraocular lenses (Rayone EMV and Vivinex Impress XY1-EM) to see which provides better vision at intermediate distances after cataract surgery. About 100 adults with age-related cataracts will receive these lenses in both eyes. The goal …

This study tests whether keeping the eye at a lower pressure during cataract surgery leads to fewer side effects and better vision in the first week after the procedure. About 105 people with cataracts will have one eye operated on with a standard-pressure system and the other wi…

This study looks at whether a multimedia education program (like videos and interactive materials) can reduce anxiety and improve self-care knowledge in people having cataract surgery. About 118 adults will be randomly assigned to receive either standard instructions or the multi…

This study tests a special lens for cataract surgery in 30 people aged 50+ who previously had LASIK for nearsightedness. The lens aims to improve vision at all distances and boost satisfaction. Researchers will measure how well patients see and how often they need glasses after s…

This study creates a registry of 300 cataract surgery patients to compare how well different artificial lenses work. Researchers will measure vision at various distances after surgery. The goal is to gather information, not to test a new treatment.

This study looks at 90 cataract patients who also have a thin scar on the retina (epiretinal membrane). Researchers want to see if a special artificial lens (functional IOL) helps them see better than a standard lens. Participants will have their vision tested before and after su…

This study compares newer laser techniques for cataract or vision correction surgery to see which causes less inflammation and helps eyes heal better. Researchers will measure natural antioxidants in tears and eye fluid before and after surgery in 1,000 adults. The goal is to fin…

This study is for people aged 65 to 85 who are having cataract surgery under general anesthesia. Researchers want to see how anesthesia changes blood pressure and eye pressure, and if frailty plays a role. The goal is to better understand these effects to improve safety for older…

This study is testing a new device that measures the eye to help plan cataract surgery. Researchers will collect data from 400 people to see how well the device works. The goal is to improve the accuracy of lens power calculations for better vision after surgery.

This study is for 150 adults having cataract or glaucoma surgery. Researchers will measure eye pressure and fluid drainage during the operation. The goal is to see if these measurements can help surgeons plan better care after surgery and reduce complications.

This study compares two surgical systems (UNITY VCS and Constellation) used during combined cataract and vitrectomy eye surgeries. Researchers will measure how efficient each system is in a real operating room, including setup and teardown time. About 180 adults needing this type…

This study looks at a new dual-mode phacoemulsification system for cataract surgery. Researchers will measure how much energy is used during surgery and how many eye cells are lost afterward. About 50 adults having age-related cataract surgery will take part. The goal is to see i…

This study tests a new imaging tool that gives surgeons a live, 3D view inside the eye during surgery. It includes up to 262 people with various eye conditions like retinal detachment, cataracts, or diabetic retinopathy, as well as healthy volunteers. The goal is to see if this t…

This study looks at fluid and tissue samples from the eyes of people with glaucoma and cataracts, compared to those with cataracts only. The goal is to find chemical and protein patterns linked to glaucoma. This could lead to better ways to diagnose or predict the disease. About …

This study tests three AI programs (ChatGPT 4o, GPT-5, and DeepSeek) to see how well they can read eye measurement reports and recommend the right lens implant for cataract patients. Researchers will compare the AI's suggestions to those made by eye doctors. No treatments are giv…

This study tests if a special headset (Apple Vision Pro) can help surgeons see better during cataract and other eye surgeries. About 30 adults having routine eye surgery will take part. The main goal is to make sure it's safe and to see how it affects the surgeon's work and comfo…

This study looks at 80 adults who already had cataract surgery and received special lenses that help with both distance and near vision. Researchers use advanced eye scans to measure how these lenses focus light inside the eye. The goal is to understand which lens design provides…

This study will use artificial intelligence to help doctors more accurately calculate the right lens power for cataract surgery in people with high myopia (severe nearsightedness). The goal is to improve vision results and reduce complications. Researchers will collect data from …

This study aims to understand how well people with high myopia (severe nearsightedness) see after cataract surgery, and what genetic or environmental factors affect their results. Researchers will compare 60,000 patients with high myopia, age-related cataracts, or other vision pr…

This study looks at three types of toric lens implants used during cataract surgery to correct astigmatism. Researchers will track how much each lens rotates over three months in 400 adults. The goal is to find which lens design stays most stable, helping doctors choose the best …