Can eye drops before cataract surgery improve vision?
NCT ID NCT06763731
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether using Systane COMPLETE eye drops before cataract surgery can improve dry eye symptoms and help with surgical planning. About 150 adults aged 20-85 with dry eye who need cataract surgery will use the drops regularly before their operation. Researchers will measure dry eye symptoms, vision, and eye surface health to see if the drops make a difference.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Systane COMPLETE eye drops
- What this could lead to
- If it works, this could show that using Systane COMPLETE before cataract surgery improves dry eye symptoms and helps achieve better vision after surgery.
- What could go wrong
- This is a small, early-phase trial with only 150 participants, so results may not apply to everyone. The main benefit is symptom relief, not a cure for dry eye.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 4
Runs after approval, following long-term safety and how well the treatment works in everyday use.
- Participants
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About 150 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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May 2024
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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20 to 85 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: The subjects aged 20-85 years, with normal cognitive function and capable of answering related questionnaires who require phacoemulsification and intraocular lens implantation under topical anaesthesia, are the eligible candidates. Exclusion Criteria: 1. Unable to answer the questions in the dry eye survey. 2. Ocular trauma or ocular surgery in the planned surgical eye, active ocular infection, and obvious abnormalities in ocular surface or eyelid margins other than MGD cause decreased visual acuity other than cataracts. 3. Dry eye signs: Corneal Fluorescein Staining CFS (+) to exclude any corneal abnormalities or epithelial defect 4. Systemic drug use, including tetracycline derivatives, antihistamines, and isotretinoin. 5. Using dry eye medication at screening stage
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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National Taiwan University Hospital
RECRUITINGTaipei, Taiwan, Taiwan
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- A simple blood draw might reveal hidden eye lymphoma
- Can a new lens make glasses obsolete after cataract surgery?
- Can a new lens design sharpen vision after macular surgery?