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Can Mix-and-Match lenses improve vision after cataract surgery?

NCT ID NCT07740590

Knowledge-focused Sponsor: Sichuan Academy of Medical Sciences Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 31, 2026 · Last updated Jul 31, 2026

Summary

This study follows adults with age-related cataracts who receive different types of intraocular lenses (IOLs) during surgery—either the same bifocal lens in both eyes or a mix of bifocal, EDOF, and monofocal lenses. Researchers will track how well patients adapt to their new vision over six months, measuring visual quality, satisfaction, and daily functioning. The goal is to understand which lens combinations offer the best visual outcomes and patient experience.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Multifocal intraocular lenses (IOLs) implanted during cataract surgery, including bifocal, EDOF, and monofocal combinations.
What this could lead to
If successful, this could help eye surgeons choose the best lens combination for each patient, improving visual satisfaction and quality of life after cataract surgery.
What could go wrong
This is an observational study, so it won't prove which lens is best. Results may vary widely between individuals, and the custom questionnaire may not capture all aspects of visual adaptation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 264 people

The number the study aims to enrol. It can still change while the study runs.

Started

Mar 2025

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients diagnosed with age-related cataracts who underwent phacoemulsification and intraocular lens (IOL) implantation

Ages

18 to 100 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18 years or older with age-related cataract requiring bilateral phacoemulsification and intraocular lens (IOL) implantation * Corneal astigmatism less than 0.75 D * Good general health and willing to complete all postoperative follow-up visits * Signed written informed consent Exclusion Criteria: * Previous ocular surgery or ocular trauma * Coexisting ocular diseases affecting visual potential, such as corneal opacity, glaucoma, macular degeneration, or diabetic retinopathy * Intraoperative or postoperative complications (e.g., posterior capsule rupture) * Systemic diseases that may interfere with visual outcomes or follow-up compliance

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Conditions

The condition(s) this trial relates to.

cataract senile cataract

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Aphakia - lens capsule present Cataract

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Sichuan Provincial People's Hospital

    RECRUITING

    Chengdu, China

More trials for these conditions

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