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Could a tiny ring improve cataract surgery for RP patients?

NCT ID NCT07126470

Disease control Sponsor: Zhongshan Ophthalmic Center, Sun Yat-sen University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether placing a capsular tension ring (CTR) during cataract surgery helps keep the artificial lens more stable in people with retinitis pigmentosa (RP). Each of the 88 participants will get the ring in one eye, while the other eye serves as a comparison. Researchers will measure lens position, vision, and complications after surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
capsular tension ring (CTR) implantation
What this could lead to
If it works, this could improve lens stability and visual outcomes for cataract patients with retinitis pigmentosa.
What could go wrong
This is a small, early-stage trial with only 88 participants. The benefit may be small or not apply to all patients, and there are standard surgical risks like infection or inflammation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 88 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2025

Expected to finish

Aug 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥ 18 years. * Clinical diagnosis of retinitis pigmentosa (RP). * Bilateral cataract meeting the indications for IOL implantation. * Willingness to participate in the study and provision of signed informed consent. Exclusion Criteria: * History of intraocular surgery. * Severe zonular weakness (e.g., zonular dialysis \>90°, lens subluxation/dislocation) * Other ocular comorbidity: such as pseudoexfoliation syndrome, ocular trauma, corneal dystrophies, uveitis, etc. * Severe systemic diseases: such as severe hypertension, diabetes, heart disease, Alzheimer's, Parkinson, etc.

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Conditions

The condition(s) this trial relates to.

cataract retinitis pigmentosa

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cataract Retinitis pigmentosa (RP)

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    3 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Shenzhen Eye Hospital

    NOT_YET_RECRUITING

    Shenzhen, Guangdong, 518040, China

  • Wuhan Aier Eye Hospital

    NOT_YET_RECRUITING

    Wuhan, Hubei, 430061, China

  • Zhongshan Ophthalmic Center, Sun Yat-sen University

    RECRUITING

    Guangzhou, Guangdong, 510623, China

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